SNRPD2 and DMTN

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SNRPD2	DMTN
Gene Name		small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	dematin actin binding protein
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Cytosol Actin Filament Plasma Membrane Endomembrane System Spectrin-associated Cytoskeleton Actin Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Cortical Cytoskeleton Platelet Dense Tubular Network Membrane Cell Projection Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	Actin Binding Receptor Binding Protein Binding Spectrin Binding Protein Self-association
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression NcRNA Metabolic Process	Protein Complex Assembly Cytoskeleton Organization Regulation Of Cell Shape Regulation Of Lamellipodium Assembly Positive Regulation Of Fibroblast Migration Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Cell-substrate Adhesion Actin Cytoskeleton Organization Positive Regulation Of Blood Coagulation Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Peptidyl-serine Phosphorylation Calcium-mediated Signaling Using Intracellular Calcium Source Calcium-mediated Signaling Using Extracellular Calcium Source Erythrocyte Development Negative Regulation Of Peptidyl-tyrosine Phosphorylation Actin Filament Bundle Assembly Regulation Of Filopodium Assembly Actin Filament Capping Negative Regulation Of Focal Adhesion Assembly Protein Secretion By Platelet Cellular Response To Calcium Ion Cellular Response To CAMP Positive Regulation Of Wound Healing Negative Regulation Of Protein Targeting To Membrane Actin Filament Reorganization Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Platelet Aggregation Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing snRNP Assembly mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		25 interactors: CEP70 CLNS1A DDX20 DMTN EEF1G EGFR GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF STRAP STXBP2 STXBP3 WDR77 ZCCHC10	13 interactors: ACTB ACTC1 APP DYNC1LI2 EPB42 GOLGA2 NEDD4L PRKACA PROCR PTOV1 SNCA SNRPD2 SPTB
Entrez ID		6633	2039
HPRD ID		03038	00506
Ensembl ID		ENSG00000125743	ENSG00000158856
Uniprot IDs		P62316	B4DI75 Q08495
PDB IDs		1B34 1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77	1QZP 1ZV6
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly RNA Splicing MRNA Processing Ribonucleoprotein Complex Biogenesis MRNA Metabolic Process RNA Processing NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Cellular Component Assembly Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Cellular Response To Estradiol Stimulus Neutrophil Mediated Immunity Neutrophil Activation Cellular Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Response To Estrogen Stimulus Cellular Process Leukocyte Degranulation Alkanesulfonate Metabolic Process Positive Regulation Of Platelet Aggregation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Protein Secretion By Platelet Calcium-mediated Signaling Using Extracellular Calcium Source Interleukin-7-mediated Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Vesicle Docking Regulation Of Epithelial Cell Proliferation Actin Filament Reorganization Membrane Docking Activation Of Phospholipase A2 Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Calcium-mediated Signaling Cell Activation Exocytosis	Immune System Process Movement Of Cell Or Subcellular Component Regulation Of Tight Junction Assembly Cellular Response To Epinephrine Stimulus Response To Epinephrine Blood Coagulation Regulation Of Protein Binding Cell Maturation Hemostasis Regulation Of Ion Homeostasis Metal Ion Homeostasis Cellular Response To Catecholamine Stimulus Platelet Activation Ion Homeostasis Regulation Of Body Fluid Levels Cell Development Negative Regulation Of Transporter Activity Negative Regulation Of Nucleotide Metabolic Process Wound Healing Chemotaxis Regulation Of Binding Locomotion Cell Activation Immune Response Response To Wounding Regulation Of Cell Junction Assembly Water Homeostasis Homeostatic Process Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Innate Immune Response Regulation Of Cardiac Muscle Contraction Regulation Of Cation Channel Activity Regulation Of Calcium Ion Transport Into Cytosol Membrane Organization Chemical Homeostasis Extracellular Matrix Organization Extracellular Structure Organization Anatomical Structure Morphogenesis Response To Interleukin-1 Regulation Of Striated Muscle Contraction Regulation Of Phospholipase Activity Negative Regulation Of Protein Polymerization Axon Guidance Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone
Tagcloud ?			apoe apolipoprotein app appl dementin developmental disrupted drosophila ectopic flies genetically glia glial hypomorphic interacted lethal lethality medulla metabolites microtubule mis named neurodegeneration neuropil orthologue rescued resembling rnai tmcc2
Tagcloud (Difference) ?			apoe apolipoprotein app appl dementin developmental disrupted drosophila ectopic flies genetically glia glial hypomorphic interacted lethal lethality medulla metabolites microtubule mis named neurodegeneration neuropil orthologue rescued resembling rnai tmcc2
Tagcloud (Intersection) ?