SNRPD2 and LSM2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
HPRD (two hybrid)

		SNRPD2	LSM2
Description		small nuclear ribonucleoprotein D2 polypeptide	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal SnRNP Complex Ribonucleoprotein Complex	P-body Nucleus Nucleoplasm Spliceosomal Complex U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding Small GTPase Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing MRNA Catabolic Process RNA Splicing
Pathways		snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway SARS-CoV-2 modulates host translation machinery	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs		Artenimol
Diseases
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Fruit consumption ( 32066663) Subcutaneous adipose tissue ( 22589738)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Rosacea symptom severity ( 29771307) Ulcerative colitis ( 28067908)
Interacting Genes		28 interacting genes: CEBPA CEP70 CINP DDX20 DMTN EEF1G EGFR FOXP1 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF SPANXN2 STRAP STXBP2 STXBP3 WDR77 ZCCHC10	39 interacting genes: BANP CBX8 CEBPA CRMP1 DNAAF11 DNAJA1 ERG28 EXOSC10 GBP2 KRT13 LGALS7 LGALS7B LNX1 LSM1 LSM12 LSM3 LSM5 LSM6 LSM7 LSM8 LZTS1 MAGEA3 MAGEA6 MEOX2 PATL1 PCM1 PNMA1 RALA REL RSRC1 SF3B2 SMN1 SNRPD2 SNRPE TEX11 TLE5 TRIM54 ZBTB16 ZNF408
Entrez ID		6633	57819
HPRD ID		03038	06282
Ensembl ID		ENSG00000125743	ENSG00000204392
Uniprot IDs		K7ERG4 P62316	Q9Y333
PDB IDs		1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9FMD 9GBW 9GC0 9GCL	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG 8H6E 8H6J 8H6K 8H6L 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Gemini Of Cajal Bodies Protein-RNA Complex Assembly RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process Spliceosomal Complex Assembly RNA Processing MRNA Splicing, Via Spliceosome Protein-containing Complex Assembly RNA Metabolic Process Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Organization Nucleic Acid Metabolic Process Nuclear Body Cytosol Cellular Component Assembly Nucleobase-containing Compound Metabolic Process U4/U6 X U5 Tri-snRNP Complex Methylosome Macromolecule Metabolic Process U2-type Precatalytic Spliceosome Nucleoplasm Tertiary Granule Spliceosomal Complex Presynaptic Dense Core Vesicle Exocytosis PICln-Sm Protein Complex Neuronal Dense Core Vesicle Exocytosis Neutrophil Degranulation Lsm2-8 Complex 7-methylguanosine Cap Hypermethylation Dense Core Granule Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter U6 SnRNP Nucleus RNA Binding U4 SnRNP Cajal Body Specific Granule Syntaxin-1 Binding Spliceosomal Tri-snRNP Complex Assembly Catalytic Step 2 Spliceosome DNA-templated Transcription Termination Precatalytic Spliceosome U1 SnRNP U5 SnRNP Secretory Granule Localization	U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions Lsm2-8 Complex U4/U6 X U5 Tri-snRNP Complex U6 SnRNP Lsm1-7-Pat1 Complex RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome Precatalytic Spliceosome MRNA Processing Spliceosomal Complex RNA Processing U12-type Spliceosomal Complex MRNA Catabolic Process RNA Metabolic Process Catalytic Step 2 Spliceosome Ribonucleoprotein Complex RNA Binding Spliceosomal Complex Assembly RNA Catabolic Process Small Nuclear Ribonucleoprotein Complex SMN-Sm Protein Complex Nucleus Nucleic Acid Metabolic Process U2-type Prespliceosome Assembly U2 SnRNP U2-type Spliceosomal Complex Nucleobase-containing Compound Metabolic Process P-body PICln-Sm Protein Complex Nuclear-transcribed MRNA Catabolic Process Nucleobase-containing Compound Catabolic Process Spliceosomal SnRNP Assembly 7-methylguanosine Cap Hypermethylation U4 SnRNP Methylosome Nuclear Speck Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA U6 SnRNA Binding Histone MRNA Catabolic Process P-body Assembly Negative Regulation Of Metabolic Process MRNA Methylguanosine-cap Decapping Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression U1 SnRNP U5 SnRNP RNA Decapping Protein Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?