SULT1E1 and PDE9A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SULT1E1	PDE9A
Gene Name		sulfotransferase family 1E, estrogen-preferring, member 1	phosphodiesterase 9A
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Estrone Sulfotransferase Activity Steroid Binding Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Xenobiotic Metabolic Process Female Pregnancy Steroid Metabolic Process Estrogen Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Signal Transduction Blood Coagulation Metabolic Process CGMP-mediated Signaling
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Platelet homeostasis Nitric oxide stimulates guanylate cyclase cGMP effects
Drugs		Cyclizine Adenosine-3\'-5\'-Diphosphate 3\'-Phosphate-Adenosine-5\'-Phosphate Sulfate 3,5,3\',5\'-Tetrachloro-Biphenyl-4,4\'-Diol
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BMPR2 C14orf1 COPS6 EEF1A1 ENOX1 IGSF21 LRIF1 PDE9A RBM48 SETDB1 SULT2B1 TP53 UNC119	18 interactors: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NL PHYHIPL SULT1E1 TRIM32 TRPV6 UTP23
Entrez ID		6783	5152
HPRD ID		08966	09115
Ensembl ID		ENSG00000109193	ENSG00000160191
Uniprot IDs		P49888 Q53X91	O76083
PDB IDs		1G3M 1HY3 4JVL 4JVM 4JVN	2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6
Enriched GO Terms of Interacting Partners?
Tagcloud ?		analyzing bovine caruncular catalyzed conflict conflicting esr esrs estrogens expresses giant placentas pools posttranscriptional produces resolve sorting sulfonation tgc tgcs transcript trophoblast unable uninucleated utc utcs virtually	acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576
Tagcloud (Difference) ?		analyzing bovine caruncular catalyzed conflict conflicting esr esrs estrogens expresses giant placentas pools posttranscriptional produces resolve sorting sulfonation tgc tgcs transcript trophoblast unable uninucleated utc utcs virtually	acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576
Tagcloud (Intersection) ?