ITPRID2 and KHDRBS1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ITPRID2	KHDRBS1
Description		ITPR interacting domain containing 2	KH RNA binding domain containing, signal transduction associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Protein-containing Complex Grb2-Sos Complex
	Molecular Function	Actin Binding Signaling Receptor Binding Protein Binding Actin Filament Binding	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Domain Specific Binding Signaling Adaptor Activity SH2 Domain Binding Identical Protein Binding Protein-containing Complex Binding Molecular Function Inhibitor Activity Protein Tyrosine Kinase Binding
	Biological Process		G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Cell Surface Receptor Signaling Pathway Spermatogenesis Regulation Of Protein Stability Regulation Of Apoptotic Process Regulation Of RNA Splicing Negative Regulation Of DNA-templated Transcription Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway Regulation Of Cell Cycle
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		8 interacting genes: ATXN7 BRCA1 FAM107A KHDRBS1 LUC7L2 PTEN SMARCA2 TSG101	116 interacting genes: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK CBL CD2AP CDC42 CDK1 CEBPA CIRBP CLK1 CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 DSCAM EFEMP1 EMG1 FGR FNBP4 FRK FXR1 FXR2 FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITPRID2 ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OGT OSTF1 PACSIN1 PALS2 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SHANK3 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SRPK2 STAT3 STUB1 TBL1X TJP1 TSPOAP1 TUBB3 UBA52 UBASH3B UBC USP7 VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6
Entrez ID		6744	10657
HPRD ID		00353	03926
Ensembl ID		ENSG00000138434	ENSG00000121774
Uniprot IDs		E7EUL7 E9PHV5 P28290	Q07666
PDB IDs			2XA6 3QHE 7Z89 7Z8A 7Z9A 7Z9B 7ZAB 7ZAC 7ZAF 7ZAM
Enriched GO Terms of Interacting Partners?		Regulation Of Growth Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Growth Regulation Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Focal Adhesion Assembly Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Organelle Organization Negative Regulation Of Mitotic Cell Cycle Molecular Function Inhibitor Activity Negative Regulation Of Growth Negative Regulation Of Cell Cycle Phase Transition Regulation Of DNA Repair Negative Regulation Of Cell-matrix Adhesion Regulation Of Microtubule-based Process Negative Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Nucleus Negative Regulation Of Cell Cycle Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell-substrate Adhesion Regulation Of Focal Adhesion Assembly Negative Regulation Of Cell Cycle G1/S Phase Transition Grb2-Sos Complex Regulation Of Protein Stability Regulation Of Cell-substrate Junction Organization Enzyme Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Histone H2AK127 Ubiquitin Ligase Activity Regulation Of Primary Metabolic Process Histone H2AK129 Ubiquitin Ligase Activity Regulation Of RNA Biosynthetic Process BRCA1-BARD1 Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Ubiquitin-dependent Endocytosis Negative Regulation Of Protein Phosphorylation Regulation Of DNA Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process	Phosphotyrosine Residue Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Cytosol Cytoplasm Intracellular Signal Transduction Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Cell-cell Junction Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Protein Tyrosine Kinase Activity Immune Response-activating Signaling Pathway Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway SH3 Domain Binding Protein Binding Activation Of Immune Response Regulation Of Intracellular Signal Transduction Antigen Receptor-mediated Signaling Pathway Plasma Membrane Regulation Of Signaling Regulation Of Cell Communication Regulation Of Signal Transduction T Cell Receptor Signaling Pathway T Cell Costimulation Regulation Of Endocytosis Fc-gamma Receptor Signaling Pathway Intracellular Signaling Cassette Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Phosphorylation Regulation Of Transport Protein Phosphorylation Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Positive Regulation Of Immune Response Regulation Of Immune System Process Positive Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Developmental Process Regulation Of Immune Response Immune System Process Ionotropic Glutamate Receptor Binding Endocytosis Negative Regulation Of Inflammatory Response To Antigenic Stimulus Ephrin Receptor Signaling Pathway
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