SSFA2 and ATXN7

Number of citations of the paper that reports this interaction (PMID 21078624)
14

Data Source:
BioGRID (two hybrid)

		SSFA2	ATXN7
Gene Name		sperm specific antigen 2	ataxin 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Cytoskeleton Nuclear Matrix
	Molecular Function	Actin Binding Receptor Binding	Chromatin Binding Protein Binding
	Biological Process		Microtubule Cytoskeleton Organization Chromatin Organization Transcription, DNA-templated Nucleus Organization Visual Perception Histone Deubiquitination Negative Regulation Of Phosphorylation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATXN7 BRCA1 KHDRBS1 LUC7L2 YWHAE YWHAG YWHAQ YWHAZ	59 interactors: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN HIST1H3A JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SSFA2 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 VCP VWF
Entrez ID		6744	6314
HPRD ID		00353	06365
Ensembl ID		ENSG00000138434	ENSG00000163635
Uniprot IDs		E9PHV5 P28290	O15265 Q9UPD8
PDB IDs			2KKR
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intracellular Transport Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Regulation Of Intracellular Transport Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Transport Regulation Of Signal Transduction Regulation Of Organelle Organization Regulation Of Signaling Apoptotic Process Protein Targeting G2/M Transition Of Mitotic Cell Cycle Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Establishment Of Protein Localization Regulation Of Apoptotic Process Regulation Of Cell Death Substantia Nigra Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Protein Localization Membrane Organization Intracellular Protein Transport Intracellular Signal Transduction Neural Nucleus Development Regulation Of Cellular Component Organization Cell Cycle Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Midbrain Development Cell Cycle Cellular Protein Localization Positive Regulation Of RNA Export From Nucleus Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Heart Rate By Hormone Protein Transport	Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Cell-substrate Junction Assembly Cell-substrate Adhesion Platelet Degranulation Cellular Localization Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Vesicle-mediated Transport Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Cell Junction Assembly Protein Localization To Tight Junction Regulation Of Metabolic Process Histone Deubiquitination Regulation Of Cellular Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Response To Wounding Regulation Of Protein Catabolic Process Regulation Of Cell Death Protein Ubiquitination Protein Polyubiquitination Blood Coagulation Cellular Protein Modification Process Hemostasis Positive Regulation Of Proteolysis Focal Adhesion Assembly Cellular Component Assembly Protein Localization Extracellular Matrix Disassembly Platelet Activation Regulation Of Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Protein Complex Assembly Regulation Of Signaling Cellular Protein Metabolic Process Protein Localization To Cell Junction Cell Death Death Response To Stress Nervous System Development Positive Regulation Of Protein Catabolic Process Secretion By Cell Substrate Adhesion-dependent Cell Spreading Adherens Junction Assembly Protein Metabolic Process
Tagcloud ?		affymetrix caloric calorie cga circadian clocks con corroborated cr detrimental genechip lived longevity macaca macaque macaques mounting mulatta neuroendocrine nonhuman peripubertal pituitary primates probesets reproduction restriction rhesus testes testicular	accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Difference) ?		affymetrix caloric calorie cga circadian clocks con corroborated cr detrimental genechip lived longevity macaca macaque macaques mounting mulatta neuroendocrine nonhuman peripubertal pituitary primates probesets reproduction restriction rhesus testes testicular	accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Intersection) ?