PDE4C

Gene Name		phosphodiesterase 4C, cAMP-specific
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytosol Primary Cilium
	Molecular Function	3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	CAMP Catabolic Process Signal Transduction
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Opioid Signalling DARPP-32 events
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: SRI
Entrez ID		5143
HPRD ID		02529
Ensembl ID		ENSG00000105650
Uniprot IDs		O43849 P78505 Q08493 Q32MM7 Q7KYS4
PDB IDs		1LXU 2QYM
Enriched GO Terms of Interacting Partners?		Intracellular Sequestering Of Iron Ion Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Relaxation Of Muscle Negative Regulation Of Heart Rate Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sequestering Of Metal Ion Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity Regulation Of Voltage-gated Calcium Channel Activity Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Heart Contraction Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Sequestering Of Protein Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Regulation Of Cardiac Muscle Cell Contraction Negative Regulation Of DNA Binding Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Insulin Secretion Negative Regulation Of Protein Import Into Nucleus Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Cation Channel Activity Positive Regulation Of Peptide Hormone Secretion Regulation Of Calcium Ion Transport Into Cytosol Positive Regulation Of Peptide Secretion Negative Regulation Of Protein Localization To Nucleus Cellular Iron Ion Homeostasis Regulation Of DNA Binding Regulation Of Striated Muscle Contraction Action Potential Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transport Negative Regulation Of Binding
Tagcloud ?