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SP3 and PIAS1
Number of citations of the paper that reports this interaction (PMID
12356736
)
71
Data Source:
HPRD
(two hybrid, in vitro)
SP3
PIAS1
Gene Name
Sp3 transcription factor
protein inhibitor of activated STAT, 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Plasma Membrane
PML Body
Transcriptional Repressor Complex
Nucleus
Nucleoplasm
PML Body
Nuclear Speck
Molecular Function
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Chromatin Binding
Double-stranded DNA Binding
Protein Binding
Metal Ion Binding
DNA Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Enzyme Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
Androgen Receptor Binding
SUMO Ligase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Ossification
Natural Killer Cell Differentiation
Trophectodermal Cell Differentiation
Liver Development
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
B Cell Differentiation
T Cell Differentiation
Megakaryocyte Differentiation
Monocyte Differentiation
Lung Development
Granulocyte Differentiation
Enucleate Erythrocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Embryonic Camera-type Eye Morphogenesis
Embryonic Skeletal System Development
Embryonic Process Involved In Female Pregnancy
Definitive Hemopoiesis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
JAK-STAT Cascade
Spermatogenesis
Protein Sumoylation
Cytokine-mediated Signaling Pathway
Androgen Receptor Signaling Pathway
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Sumoylation
Regulation Of Cell Proliferation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Smooth Muscle Cell Differentiation
Interferon-gamma-mediated Signaling Pathway
Regulation Of Interferon-gamma-mediated Signaling Pathway
Protein-DNA Complex Assembly
Pathways
Interferon gamma signaling
Interferon Signaling
Cytokine Signaling in Immune system
Regulation of IFNG signaling
Drugs
Diseases
GWAS
Major depressive disorder (
23377640
)
Protein-Protein Interactions
19 interactors:
E2F1
EP300
ESR1
GABPA
GCH1
GRIN1
HDAC1
HDAC2
HLTF
NKX3-1
PIAS1
RB1
RBBP4
SP1
STK19
SUMO1
TP53
UBE2I
ZBTB7A
92 interactors:
AKT1
AR
ATXN1
AXIN1
BARD1
BRCA1
CARM1
CASP8
CBS
CEBPA
CEBPE
CHUK
CREB1
CREBBP
CSNK2A1
CSRP2
DCLRE1A
DDX21
DDX5
DNM1
DNMT3A
ELK3
ESR1
ESR2
FLI1
GATA4
GLUL
GRM8
HIC1
HTT
JUN
L3MBTL2
MAML1
MBD1
MDC1
MDM2
MITF
MSX1
MX1
MYB
NCOR1
NFATC1
NIN
NR2F2
NR3C2
NR5A1
PAXIP1
PGR
PIAS2
PIAS4
PLAG1
PML
PPP1CA
PPP1CC
PRDM1
PRMT1
PRMT6
PRPF40A
PTK2
PTPN1
RAD54L2
RBBP6
RELA
SATB1
SATB2
SERBP1
SGTA
SIAH1
SIAH2
SKIL
SMAD1
SMAD4
SMAD7
SNIP1
SP3
SPOP
SREBF2
STAT1
SUFU
SUMO1
SUMO2
SUMO3
TBP
TP53
TP73
TRIM27
TRIM55
TRIM63
UBE2I
YWHAZ
ZNF451
ZNF76
Entrez ID
6670
8554
HPRD ID
03483
16029
Ensembl ID
ENSG00000172845
ENSG00000033800
Uniprot IDs
B7ZLN9
Q02447
Q59FX5
Q86TP0
O75925
Q1XBU8
PDB IDs
1V66
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Rhythmic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Chromatin Organization
Regulation Of Signaling
Response To Organic Substance
Biosynthetic Process
Cellular Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signal Transduction
Chromatin Modification
Regulation Of Cell Cycle
Chromatin Remodeling
Intracellular Steroid Hormone Receptor Signaling Pathway
Cellular Response To Organic Substance
Chromosome Organization
Regulation Of Cell Proliferation
Mitotic Cell Cycle
Cellular Response To Hypoxia
Negative Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
RNA Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Cellular Response To Organic Substance
Macromolecule Biosynthetic Process
Response To Organic Substance
Cellular Response To Stimulus
Regulation Of Cellular Process
Multicellular Organismal Development
Biosynthetic Process
Response To Stimulus
Regulation Of Signaling
Cell Differentiation
Organ Development
Signaling
Signal Transduction
Anatomical Structure Development
Developmental Process
Regulation Of Signal Transduction
Tagcloud
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
gtf2f1
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Difference)
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
gtf2f1
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Intersection)
?