SP3 and ZBTB7A

Number of citations of the paper that reports this interaction (PMID 12004059)
24

Data Source:
HPRD (in vitro)

		SP3	ZBTB7A
Gene Name		Sp3 transcription factor	zinc finger and BTB domain containing 7A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane PML Body Transcriptional Repressor Complex	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Double-stranded DNA Binding Protein Binding Metal Ion Binding	DNA Binding Protein Binding Histone Acetyltransferase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ossification Natural Killer Cell Differentiation Trophectodermal Cell Differentiation Liver Development Embryonic Placenta Development Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter B Cell Differentiation T Cell Differentiation Megakaryocyte Differentiation Monocyte Differentiation Lung Development Granulocyte Differentiation Enucleate Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Camera-type Eye Morphogenesis Embryonic Skeletal System Development Embryonic Process Involved In Female Pregnancy Definitive Hemopoiesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: E2F1 EP300 ESR1 GABPA GCH1 GRIN1 HDAC1 HDAC2 HLTF NKX3-1 PIAS1 RB1 RBBP4 SP1 STK19 SUMO1 TP53 UBE2I ZBTB7A	12 interactors: AR BCL6 HOMEZ KHDRBS1 RELA SP1 SP3 SP4 SUMO1 TP53 ZBTB48 ZMYND8
Entrez ID		6670	51341
HPRD ID		03483	10433
Ensembl ID		ENSG00000172845	ENSG00000178951
Uniprot IDs		B7ZLN9 Q02447 Q59FX5 Q86TP0	O95365 Q8TB76
PDB IDs			2IF5 2NN2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Rhythmic Process RNA Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Organization Regulation Of Signaling Response To Organic Substance Biosynthetic Process Cellular Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Signal Transduction Chromatin Modification Regulation Of Cell Cycle Chromatin Remodeling Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Chromosome Organization Regulation Of Cell Proliferation Mitotic Cell Cycle Cellular Response To Hypoxia	Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Embryonic Process Involved In Female Pregnancy B Cell Differentiation Erythrocyte Differentiation Enucleate Erythrocyte Differentiation Erythrocyte Homeostasis Positive Regulation Of Histone Deacetylation Myeloid Cell Homeostasis Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Megakaryocyte Differentiation Positive Regulation Of Protein Deacetylation Liver Development B Cell Activation Definitive Hemopoiesis Positive Regulation Of Cellular Biosynthetic Process Trophectodermal Cell Differentiation Protein Localization To Nucleus Gland Development Protein Import Into Nucleus, Translocation
Tagcloud ?			acquisition actionable ar block bypassed castration conversely counteracts crpc driven elucidate facilitates identifies innovative integrated leverages mechanistically notably overcomes predictive prostate pten signature srd5a1 stratification tailored trp53 xaf1 xiap
Tagcloud (Difference) ?			acquisition actionable ar block bypassed castration conversely counteracts crpc driven elucidate facilitates identifies innovative integrated leverages mechanistically notably overcomes predictive prostate pten signature srd5a1 stratification tailored trp53 xaf1 xiap
Tagcloud (Intersection) ?