RABGGTA

Description		Rab geranylgeranyltransferase subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	Prenyltransferase Activity Protein Geranylgeranyltransferase Activity Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Protein Prenyltransferase Activity Transferase Activity Small GTPase Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Visual Perception Protein Geranylgeranylation Protein Modification Process
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS
Interacting Genes		2 interacting genes: BMPR2 RAB1A
Entrez ID		5875
HPRD ID		03547
Ensembl ID		ENSG00000100949
Uniprot IDs		Q92696
PDB IDs
Enriched GO Terms of Interacting Partners?		Cadherin Binding Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis Growth Hormone Secretion Virion Assembly Maternal Placenta Development Lung Vasculature Development Pharyngeal Arch Artery Morphogenesis Endothelial Cell Apoptotic Process Transmembrane Receptor Protein Serine/threonine Kinase Activity Negative Regulation Of Vasoconstriction Endocardial Cushion Development Regulation Of Axon Extension Involved In Axon Guidance Lymphangiogenesis Retina Vasculature Development In Camera-type Eye Atrial Septum Morphogenesis Establishment Of Endothelial Intestinal Barrier Heart Valve Development BMP Binding Regulation Of Cell Proliferation Involved In Heart Morphogenesis Atrioventricular Valve Morphogenesis Cell Development Chondrocyte Development Negative Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Glycoprotein Metabolic Process Establishment Of Melanosome Localization Melanosome Localization COPII-coated Vesicle Cargo Loading Melanosome Transport Pigment Granule Transport Pigment Granule Localization Outflow Tract Septum Morphogenesis Endothelial Cell Differentiation Activin Receptor Signaling Pathway Cellular Response To BMP Stimulus Positive Regulation Of Cartilage Development
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