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BMPR1B and SNX6
Number of citations of the paper that reports this interaction (PMID
11279102
)
30
Data Source:
HPRD
(in vitro, in vivo)
BMPR1B
SNX6
Gene Name
bone morphogenetic protein receptor, type IB
sorting nexin 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Receptor Complex
Intracellular
Nucleus
Cytoplasm
Cytoplasmic Membrane-bounded Vesicle
Extrinsic Component Of Membrane
Retromer Complex
Early Endosome Membrane
Tubular Endosome
Molecular Function
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta Receptor Activity, Type I
Protein Binding
ATP Binding
SMAD Binding
Metal Ion Binding
Protein Binding
Dynactin Binding
Phosphatidylinositol Binding
Protein Homodimerization Activity
Biological Process
Skeletal System Development
Cartilage Condensation
Ovarian Cumulus Expansion
Eye Development
Chondrocyte Development
Protein Phosphorylation
Inflammatory Response
Dorsal/ventral Pattern Formation
Signal Transduction By Phosphorylation
Proteoglycan Biosynthetic Process
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Retinal Ganglion Cell Axon Guidance
Limb Morphogenesis
Ovulation Cycle
Positive Regulation Of Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Retina Development In Camera-type Eye
Endochondral Bone Morphogenesis
Positive Regulation Of Cartilage Development
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Chondrocyte Proliferation
Intracellular Protein Transport
Endocytosis
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Vesicle Organization
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Retrograde Transport, Endosome To Golgi
Negative Regulation Of Transcription, DNA-templated
Regulation Of Histamine Secretion By Mast Cell
Pathways
Signaling by BMP
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
20732626
)
Protein-Protein Interactions
63 interactors:
AMHR2
APP
ARHGEF6
BAMBI
BMP15
BMP2
BMP4
BMP6
BMP7
BMPR1A
BMPR2
CDK14
CDK4
CHN1
DCAF12
DCAF6
DCAF7
FANCL
GDF5
GDF6
GDF9
KLHL1
LZTR1
NKIRAS1
OXSR1
PAK1
PLEKHB1
POMK
PPP2CA
PPP3CC
RAB25
RAB38
RAB6B
RAN
RAP2A
RASD2
RASL12
RHEBL1
RHOD
RHOJ
RPS27A
RRAS2
SASH3
SH3KBP1
SMAD6
SMAD7
SNX6
SOCS6
SQSTM1
SRGAP1
STAMBP
STK35
STUB1
TGFBR1
TNNT1
TRAF6
TTC17
TTC27
UBA52
UBE2Z
UBXN1
USP45
VEPH1
22 interactors:
ACVR2B
ACVRL1
BMPR1B
BRCA1
BRMS1
CALM1
COIL
CSNK2A2
DISC1
EGFR
INSR
LEPR
NDEL1
PDGFRA
PIM1
SNX1
SNX2
SNX4
TGFBR1
TGFBR2
TNIK
TPT1
Entrez ID
658
58533
HPRD ID
04457
12086
Ensembl ID
ENSG00000138696
ENSG00000129515
Uniprot IDs
A8KAE3
O00238
B4DJS7
Q9UNH7
PDB IDs
3MDY
Enriched GO Terms of Interacting Partners
?
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
BMP Signaling Pathway
Intracellular Signal Transduction
Regulation Of Signal Transduction
Signal Transduction
Signaling
Regulation Of Protein Phosphorylation
Regulation Of Signaling
Cell Communication
Positive Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Positive Regulation Of Protein Modification Process
Regulation Of Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Regulation Of Phosphorus Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Response To Growth Factor
Positive Regulation Of Protein Phosphorylation
Cellular Response To Transforming Growth Factor Beta Stimulus
SMAD Protein Signal Transduction
Response To Transforming Growth Factor Beta
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Phosphorylation
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Stimulus
Small GTPase Mediated Signal Transduction
Regulation Of MAPK Cascade
Cellular Protein Modification Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Signal Transduction By Phosphorylation
Regulation Of Cell Development
Regulation Of Cellular Process
Regulation Of Cell Death
Negative Regulation Of Signal Transduction
Regulation Of Apoptotic Process
Phosphorylation
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction By Phosphorylation
Regulation Of Signaling
Developmental Process
Positive Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
Positive Regulation Of Transferase Activity
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phosphorylation
Protein Phosphorylation
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Metabolic Process
Anatomical Structure Development
Phosphorylation
Intracellular Signal Transduction
Regulation Of Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Development
Regulation Of Phosphorylation
Activation Of Protein Kinase Activity
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Anatomical Structure Morphogenesis
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Catalytic Activity
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Differentiation
Cellular Protein Modification Process
Cellular Response To Growth Factor Stimulus
Regulation Of Metabolic Process
Sensory Organ Development
Camera-type Eye Development
Response To Growth Factor
Positive Regulation Of Signal Transduction
Retina Vasculature Development In Camera-type Eye
Eye Development
Phosphate-containing Compound Metabolic Process
Protein Autophosphorylation
Regulation Of Catalytic Activity
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Cell Proliferation
Palate Development
Activin Receptor Signaling Pathway
Chordate Embryonic Development
Embryo Development
Tagcloud
?
125b
acvr1b
acvr2a
arid3b
bak1
bcl2l2
bear
bim
cadm1
cardio
cardiology
cmass
e2f3
fgfr2
fgfr3
glut3
il6r
jph2
men1
mirs
onco
orchestration
raf1
sitr7
smoothened
st7l
twist1
wee1
wnt7a
Tagcloud (Difference)
?
125b
acvr1b
acvr2a
arid3b
bak1
bcl2l2
bear
bim
cadm1
cardio
cardiology
cmass
e2f3
fgfr2
fgfr3
glut3
il6r
jph2
men1
mirs
onco
orchestration
raf1
sitr7
smoothened
st7l
twist1
wee1
wnt7a
Tagcloud (Intersection)
?