BMPR1B and AMHR2

Number of citations of the paper that reports this interaction (PMID 11420127)
14

Data Source:
HPRD (in vivo)

		BMPR1B	AMHR2
Gene Name		bone morphogenetic protein receptor, type IB	anti-Mullerian hormone receptor, type II
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Integral Component Of Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Receptor Activity, Type I Protein Binding ATP Binding SMAD Binding Metal Ion Binding	Receptor Signaling Protein Serine/threonine Kinase Activity Receptor Activity Transforming Growth Factor Beta Receptor Activity, Type II Protein Binding ATP Binding Hormone Binding Metal Ion Binding Anti-Mullerian Hormone Receptor Activity
	Biological Process	Skeletal System Development Cartilage Condensation Ovarian Cumulus Expansion Eye Development Chondrocyte Development Protein Phosphorylation Inflammatory Response Dorsal/ventral Pattern Formation Signal Transduction By Phosphorylation Proteoglycan Biosynthetic Process Positive Regulation Of Bone Mineralization BMP Signaling Pathway Retinal Ganglion Cell Axon Guidance Limb Morphogenesis Ovulation Cycle Positive Regulation Of Cell Differentiation Positive Regulation Of Osteoblast Differentiation Retina Development In Camera-type Eye Endochondral Bone Morphogenesis Positive Regulation Of Cartilage Development Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Chondrocyte Proliferation	Mullerian Duct Regression Protein Phosphorylation Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Sex Differentiation Signal Transduction By Phosphorylation Negative Regulation Of Anti-Mullerian Hormone Signaling Pathway Anti-Mullerian Hormone Signaling Pathway
Pathways		Signaling by BMP
Drugs			Adenosine triphosphate
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732626)
Protein-Protein Interactions		63 interactors: AMHR2 APP ARHGEF6 BAMBI BMP15 BMP2 BMP4 BMP6 BMP7 BMPR1A BMPR2 CDK14 CDK4 CHN1 DCAF12 DCAF6 DCAF7 FANCL GDF5 GDF6 GDF9 KLHL1 LZTR1 NKIRAS1 OXSR1 PAK1 PLEKHB1 POMK PPP2CA PPP3CC RAB25 RAB38 RAB6B RAN RAP2A RASD2 RASL12 RHEBL1 RHOD RHOJ RPS27A RRAS2 SASH3 SH3KBP1 SMAD6 SMAD7 SNX6 SOCS6 SQSTM1 SRGAP1 STAMBP STK35 STUB1 TGFBR1 TNNT1 TRAF6 TTC17 TTC27 UBA52 UBE2Z UBXN1 USP45 VEPH1	3 interactors: AMH BMPR1B TGFBR1
Entrez ID		658	269
HPRD ID		04457	02978
Ensembl ID		ENSG00000138696	ENSG00000135409
Uniprot IDs		A8KAE3 O00238	Q16671
PDB IDs		3MDY
Enriched GO Terms of Interacting Partners?		Regulation Of Pathway-restricted SMAD Protein Phosphorylation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation BMP Signaling Pathway Intracellular Signal Transduction Regulation Of Signal Transduction Signal Transduction Signaling Regulation Of Protein Phosphorylation Regulation Of Signaling Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Phosphorus Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Metabolic Process Response To Growth Factor Positive Regulation Of Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus SMAD Protein Signal Transduction Response To Transforming Growth Factor Beta Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Stimulus Small GTPase Mediated Signal Transduction Regulation Of MAPK Cascade Cellular Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Signal Transduction By Phosphorylation Regulation Of Cell Development Regulation Of Cellular Process Regulation Of Cell Death Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Phosphorylation	Oogenesis Stage Gonad Development Development Of Primary Sexual Characteristics Sex Differentiation Reproductive Structure Development Reproductive System Development Gamete Generation Ovarian Follicle Development Developmental Process Involved In Reproduction Oogenesis Sexual Reproduction Multicellular Organismal Reproductive Process Regulation Of Cartilage Development Multicellular Organism Reproduction Ovulation Cycle Process Female Gonad Development Female Gamete Generation Ovulation Cycle Development Of Primary Female Sexual Characteristics Reproduction Single Organism Reproductive Process Reproductive Process Male Sex Differentiation Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Mesenchyme Development Ovarian Cumulus Expansion Preantral Ovarian Follicle Growth Negative Regulation Of Chondrocyte Proliferation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Germ Cell Development Skeletal System Morphogenesis Tissue Development Signal Transduction By Phosphorylation Cell Development Rhythmic Process Camera-type Eye Development Urogenital System Development Antral Ovarian Follicle Growth Eye Development Gonadal Mesoderm Development Mullerian Duct Regression Parathyroid Gland Development Anatomical Structure Morphogenesis Pattern Specification Process Endothelial Cell Activation Skeletal System Development Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus Sensory Organ Development
Tagcloud ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a	34b 34c 7b adenocarcinomas advantages cdkn1c cre created dicer dko dramatic fallopian fl implicating let microrna mir mirnas mybl2 originating phenocopied pten serous synergize transcriptionally tubes tumorigenesis uncover warranted
Tagcloud (Difference) ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a	34b 34c 7b adenocarcinomas advantages cdkn1c cre created dicer dko dramatic fallopian fl implicating let microrna mir mirnas mybl2 originating phenocopied pten serous synergize transcriptionally tubes tumorigenesis uncover warranted
Tagcloud (Intersection) ?