BMPR1B and RAB38

Number of citations of the paper that reports this interaction (PMID 15761153)
154

Data Source:
HPRD (in vivo)

		BMPR1B	RAB38
Gene Name		bone morphogenetic protein receptor, type IB	RAB38, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Early Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Phagocytic Vesicle Membrane Early Endosome Lumen Melanosome Phagocytic Vesicle
	Molecular Function	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Receptor Activity, Type I Protein Binding ATP Binding SMAD Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding AP-2 Adaptor Complex Binding AP-1 Adaptor Complex Binding AP-3 Adaptor Complex Binding BLOC-2 Complex Binding
	Biological Process	Skeletal System Development Cartilage Condensation Ovarian Cumulus Expansion Eye Development Chondrocyte Development Protein Phosphorylation Inflammatory Response Dorsal/ventral Pattern Formation Signal Transduction By Phosphorylation Proteoglycan Biosynthetic Process Positive Regulation Of Bone Mineralization BMP Signaling Pathway Retinal Ganglion Cell Axon Guidance Limb Morphogenesis Ovulation Cycle Positive Regulation Of Cell Differentiation Positive Regulation Of Osteoblast Differentiation Retina Development In Camera-type Eye Endochondral Bone Morphogenesis Positive Regulation Of Cartilage Development Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Chondrocyte Proliferation	Intracellular Protein Transport Small GTPase Mediated Signal Transduction Protein Transport Rab Protein Signal Transduction Endosome To Melanosome Transport Platelet Dense Granule Organization Protein Localization To Membrane Phagosome Acidification Melanosome Assembly
Pathways		Signaling by BMP
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732626)	Multiple sclerosis (age of onset) ( 19010793)
Protein-Protein Interactions		63 interactors: AMHR2 APP ARHGEF6 BAMBI BMP15 BMP2 BMP4 BMP6 BMP7 BMPR1A BMPR2 CDK14 CDK4 CHN1 DCAF12 DCAF6 DCAF7 FANCL GDF5 GDF6 GDF9 KLHL1 LZTR1 NKIRAS1 OXSR1 PAK1 PLEKHB1 POMK PPP2CA PPP3CC RAB25 RAB38 RAB6B RAN RAP2A RASD2 RASL12 RHEBL1 RHOD RHOJ RPS27A RRAS2 SASH3 SH3KBP1 SMAD6 SMAD7 SNX6 SOCS6 SQSTM1 SRGAP1 STAMBP STK35 STUB1 TGFBR1 TNNT1 TRAF6 TTC17 TTC27 UBA52 UBE2Z UBXN1 USP45 VEPH1	7 interactors: APP BMPR1B SMAD1 SMAD2 SMAD3 SMAD4 TGFBR1
Entrez ID		658	23682
HPRD ID		04457	05889
Ensembl ID		ENSG00000138696	ENSG00000123892
Uniprot IDs		A8KAE3 O00238	P57729
PDB IDs		3MDY
Enriched GO Terms of Interacting Partners?		Regulation Of Pathway-restricted SMAD Protein Phosphorylation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation BMP Signaling Pathway Intracellular Signal Transduction Regulation Of Signal Transduction Signal Transduction Signaling Regulation Of Protein Phosphorylation Regulation Of Signaling Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Phosphorus Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Metabolic Process Response To Growth Factor Positive Regulation Of Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus SMAD Protein Signal Transduction Response To Transforming Growth Factor Beta Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Stimulus Small GTPase Mediated Signal Transduction Regulation Of MAPK Cascade Cellular Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Signal Transduction By Phosphorylation Regulation Of Cell Development Regulation Of Cellular Process Regulation Of Cell Death Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Phosphorylation	SMAD Protein Complex Assembly Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Pattern Specification Process Response To Transforming Growth Factor Beta Growth Regulation Of Epithelial To Mesenchymal Transition Regulation Of Binding Negative Regulation Of Cell Proliferation Embryonic Pattern Specification Developmental Growth Regulation Of Cartilage Development Regulation Of Cell Differentiation Kidney Development Renal System Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Cell Development Mesonephros Development Enzyme Linked Receptor Protein Signaling Pathway Urogenital System Development Production Of MiRNAs Involved In Gene Silencing By MiRNA Mesoderm Development Positive Regulation Of Epithelial To Mesenchymal Transition Kidney Epithelium Development Regulation Of Cell Morphogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Activin Receptor Signaling Pathway Heart Development Gastrulation Gene Silencing By MiRNA Positive Regulation Of Cartilage Development Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To DsRNA Anatomical Structure Morphogenesis Skeletal System Development Cellular Response To Growth Factor Stimulus Mesenchyme Development Posttranscriptional Gene Silencing Response To Growth Factor Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Stem Cell Differentiation Embryonic Morphogenesis SMAD Protein Signal Transduction Anterior/posterior Pattern Specification Regulation Of Cell Proliferation
Tagcloud ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a	aminoterminus autophagic closest coil coiled endosomal endosomes fractionation gfp golgi gtpase gtpases heritable homologue leucine lrrk2 melanogenesis melanogenic mvbs organize perinuclear phagocytosis rab32 rab7 recycling sorting subcellular transport vesicles
Tagcloud (Difference) ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a	aminoterminus autophagic closest coil coiled endosomal endosomes fractionation gfp golgi gtpase gtpases heritable homologue leucine lrrk2 melanogenesis melanogenic mvbs organize perinuclear phagocytosis rab32 rab7 recycling sorting subcellular transport vesicles
Tagcloud (Intersection) ?