AMHR2

Name	anti-Mullerian hormone receptor type 2
Structure
Novel Interactors	2 novel interactors: TUBA1A TUBA1C
Interactors	4 interactors: AMH BMPR1B MAL TGFBR1
GO Annotations	Cellular Component	Plasma Membrane Membrane Receptor Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Receptor Activity Transforming Growth Factor Beta Receptor Activity, Type II Protein Binding ATP Binding Kinase Activity Transferase Activity Hormone Binding Protein Homodimerization Activity Metal Ion Binding Anti-Mullerian Hormone Receptor Activity
	Biological Process	Mullerian Duct Regression Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Sex Differentiation Male Gonad Development Female Gonad Development BMP Signaling Pathway Cellular Response To Growth Factor Stimulus Anti-Mullerian Hormone Receptor Signaling Pathway
Pathways	Signaling by BMP
Drugs	ATP
Diseases	46,XY disorders of sex development (Other), including: Persistent Mullerian duct syndrome; Hypospadias; Cryptorchidism
GWAS	No GWAS studies recorded
Entrez ID	269
HPRD ID	02978
Ensembl ID	ENSG00000135409
Uniprot IDs	Q16671
PDB IDs	7L0J
GO Terms Enriched among Interactors ?	Transforming Growth Factor Beta Receptor Activity, Type I Type II Transforming Growth Factor Beta Receptor Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Ovulation Cycle Process Positive Regulation Of SMAD Protein Signal Transduction Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors SMAD Binding Regulation Of Chondrocyte Differentiation Mesenchyme Development Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cytoplasmic Microtubule Regulation Of Apoptotic Signaling Pathway Regulation Of SMAD Protein Signal Transduction Cell Differentiation Regulation Of Cartilage Development Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Reproductive Process Negative Regulation Of Ovarian Follicle Development Cellular Developmental Process Preantral Ovarian Follicle Growth Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Cilium Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Structural Constituent Of Cytoskeleton Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Gonad Development Central Nervous System Neuron Differentiation Membrane Raft Polarization Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Mitotic Cell Cycle Mullerian Duct Regression Nucleotide Binding Ovarian Cumulus Expansion Protein Localization To Paranode Region Of Axon Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Positive Regulation Of Tight Junction Disassembly Positive Regulation Of Cell Communication Positive Regulation Of Signaling Anti-Mullerian Hormone Receptor Signaling Pathway