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WNK1 and ZNF106
Number of citations of the paper that reports this interaction (PMID
20936779
)
48
Data Source:
BioGRID
(two hybrid)
WNK1
ZNF106
Gene Name
WNK lysine deficient protein kinase 1
zinc finger protein 106
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Nucleolus
Cytosol
Membrane
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Chloride Channel Inhibitor Activity
Phosphatase Binding
Opioid Peptide Activity
SH3 Domain Binding
Poly(A) RNA Binding
Metal Ion Binding
Biological Process
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Ion Transport
Negative Regulation Of Phosphatase Activity
Peptidyl-threonine Phosphorylation
Intracellular Signal Transduction
Neuron Development
Regulation Of Cellular Process
Insulin Receptor Signaling Pathway
Pathways
Ion channel transport
Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
ADRB2
AKT1
ARAF
ATP8
ATXN1
BAG3
CLTC
COPS5
CSDE1
E2F3
FHL3
FLNC
GLIS2
KLHL2
MAP2K1
MAP3K2
MAP3K3
NEDD4L
PFKP
PRKAR1A
PRKAR1B
PVR
RANBP9
RBX1
SLC9A1
SUMO1
SYT2
TNRC6A
TSC22D1
UBC
UPF2
WNK2
YWHAE
YWHAG
YWHAZ
ZNF106
ZYX
4 interactors:
APC
SKIL
UBE2I
WNK1
Entrez ID
65125
64397
HPRD ID
05570
10317
Ensembl ID
ENSG00000060237
ENSG00000103994
Uniprot IDs
A5D8Z4
F5GWT4
H6WZW3
Q9H4A3
Q9H2Y7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Signaling
Regulation Of Phosphorus Metabolic Process
Regulation Of Signal Transduction
Regulation Of Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Sodium Ion Transport
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cellular Response To Growth Factor Stimulus
Activation Of Protein Kinase Activity
Epidermal Growth Factor Receptor Signaling Pathway
Intracellular Transport
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Protein Localization
Positive Regulation Of Sodium Ion Transport
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Response To Growth Factor
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Fibroblast Growth Factor Stimulus
Positive Regulation Of Protein Kinase Activity
Response To Fibroblast Growth Factor
Cellular Response To Peptide
Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Kinase Activity
Establishment Of Localization In Cell
Signal Transduction
Cell Communication
Cellular Localization
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Transferase Activity
Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Intracellular Signal Transduction
Positive Regulation Of Mitochondrion Organization
Cellular Response To Organic Substance
Regulation Of Cellular Localization
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Response To Abiotic Stimulus
Positive Regulation Of Phosphorylation
Cellular Response To Mechanical Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of SUMO Transferase Activity
Cell Cycle Arrest
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Cell Cycle Process
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Kinase Activity
Positive Regulation Of Signal Transduction
Negative Regulation Of Odontogenesis
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cell Cycle
Negative Regulation Of Pancreatic Juice Secretion
Positive Regulation Of Cell Projection Organization
Negative Regulation Of Transferase Activity
Mitotic Nuclear Division
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Generation Of Neurons
Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process
Neurogenesis
Camera-type Eye Development
Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Phosphorylation
Eye Development
Cell Division
Protein Heterotrimerization
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Positive Regulation Of Microtubule Polymerization
Negative Regulation Of Cell Cycle
Positive Regulation Of Systemic Arterial Blood Pressure
Positive Regulation Of Pseudopodium Assembly
Regulation Of Cell Projection Organization
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Homotrimerization
Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Nervous System Development
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Positive Regulation Of Apoptotic Process
Sensory Organ Development
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Catalytic Activity
Positive Regulation Of Cell Death
Protein Catabolic Process
Muscle Cell Cellular Homeostasis
Tagcloud
?
alanine
associate
cation
ccc
cccs
chloride
compromise
cotransporters
disruption
hence
knock
lens
lenses
maintain
opacification
osr1
proline
rat
regionally
spak
ste20
subcellular
subcellularly
susceptibility
transcript
transcriptase
transparency
wet
Tagcloud (Difference)
?
alanine
associate
cation
ccc
cccs
chloride
compromise
cotransporters
disruption
hence
knock
lens
lenses
maintain
opacification
osr1
proline
rat
regionally
spak
ste20
subcellular
subcellularly
susceptibility
transcript
transcriptase
transparency
wet
Tagcloud (Intersection)
?