ZNF106 and WNK1

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		ZNF106	WNK1
Gene Name		zinc finger protein 106	WNK lysine deficient protein kinase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytosol Membrane	Cytoplasm
	Molecular Function	Opioid Peptide Activity SH3 Domain Binding Poly(A) RNA Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Chloride Channel Inhibitor Activity Phosphatase Binding
	Biological Process	Insulin Receptor Signaling Pathway	Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Ion Transport Negative Regulation Of Phosphatase Activity Peptidyl-threonine Phosphorylation Intracellular Signal Transduction Neuron Development Regulation Of Cellular Process
Pathways			Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APC SKIL UBE2I WNK1	37 interactors: ADRB2 AKT1 ARAF ATP8 ATXN1 BAG3 CLTC COPS5 CSDE1 E2F3 FHL3 FLNC GLIS2 KLHL2 MAP2K1 MAP3K2 MAP3K3 NEDD4L PFKP PRKAR1A PRKAR1B PVR RANBP9 RBX1 SLC9A1 SUMO1 SYT2 TNRC6A TSC22D1 UBC UPF2 WNK2 YWHAE YWHAG YWHAZ ZNF106 ZYX
Entrez ID		64397	65125
HPRD ID		10317	05570
Ensembl ID		ENSG00000103994	ENSG00000060237
Uniprot IDs		Q9H2Y7	A5D8Z4 F5GWT4 H6WZW3 Q9H4A3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Positive Regulation Of SUMO Transferase Activity Cell Cycle Arrest Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cell Cycle Process Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Negative Regulation Of Odontogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cell Cycle Negative Regulation Of Pancreatic Juice Secretion Positive Regulation Of Cell Projection Organization Negative Regulation Of Transferase Activity Mitotic Nuclear Division Negative Regulation Of Protein Phosphorylation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Metaphase/anaphase Transition Of Mitotic Cell Cycle Generation Of Neurons Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Neurogenesis Camera-type Eye Development Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Phosphorylation Eye Development Cell Division Protein Heterotrimerization Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Negative Regulation Of Cell Cycle Positive Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Projection Organization Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Homotrimerization Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Nervous System Development Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Apoptotic Process Sensory Organ Development Positive Regulation Of Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Catalytic Activity Positive Regulation Of Cell Death Protein Catabolic Process Muscle Cell Cellular Homeostasis	Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Sodium Ion Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Intracellular Transport Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Sodium Ion Transport Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Growth Factor Cellular Response To Peptide Hormone Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Protein Kinase Activity Response To Fibroblast Growth Factor Cellular Response To Peptide Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Kinase Activity Establishment Of Localization In Cell Signal Transduction Cell Communication Cellular Localization Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Intracellular Signal Transduction Positive Regulation Of Mitochondrion Organization Cellular Response To Organic Substance Regulation Of Cellular Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Regulation Of MAPK Cascade Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Phosphorylation Cellular Response To Mechanical Stimulus Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?			alanine associate cation ccc cccs chloride compromise cotransporters disruption hence knock lens lenses maintain opacification osr1 proline rat regionally spak ste20 subcellular subcellularly susceptibility transcript transcriptase transparency wet
Tagcloud (Difference) ?			alanine associate cation ccc cccs chloride compromise cotransporters disruption hence knock lens lenses maintain opacification osr1 proline rat regionally spak ste20 subcellular subcellularly susceptibility transcript transcriptase transparency wet
Tagcloud (Intersection) ?