RSRC2 and UPF2

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		RSRC2	UPF2
Gene Name		arginine/serine-rich coiled-coil 2	UPF2 regulator of nonsense transcripts homolog (yeast)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Cytosol Exon-exon Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Poly(A) RNA Binding	RNA Binding Protein Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Gene Expression Organ Regeneration
Pathways			Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		13 interactors: APP CCDC155 CMTM5 GOLGA2 PNMA1 RINT1 SRPK1 SRPK2 TRIM23 TRIM54 UBQLN1 UBQLN4 UPF2	75 interactors: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GLTSCR2 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MYB NDUFA7 NOB1 NOMO1 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SKIV2L2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44
Entrez ID		65117	26019
HPRD ID		13342	10405
Ensembl ID		ENSG00000111011	ENSG00000151461
Uniprot IDs		B3KMH4 Q7L4I2	Q9HAU5
PDB IDs			1UW4 2WJV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Genome Replication MRNA Metabolic Process Negative Regulation Of Viral Genome Replication Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Chromosome Localization To Nuclear Envelope Involved In Synapsis Nuclear Speck Organization Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Regulation Of MRNA Processing Synaptic Growth At Neuromuscular Junction Regulation Of RNA Splicing MRNA Processing Collateral Sprouting In Absence Of Injury Nucleus Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Protein Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Viral Process RNA Processing	Nuclear-transcribed MRNA Catabolic Process RNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Macromolecule Catabolic Process Gene Expression Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Catabolic Process Histone MRNA Catabolic Process RRNA Processing Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Translational Initiation Viral Process Ribosome Biogenesis Biosynthetic Process Histone MRNA Metabolic Process Cellular Metabolic Process Translational Termination Protein Complex Disassembly Translational Elongation RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Protein Complex Disassembly Viral Transcription NcRNA Metabolic Process SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Metabolic Process Establishment Of Protein Localization To Membrane Translation Protein Targeting To Membrane Nuclear MRNA Surveillance Protein Localization To Membrane
Tagcloud ?		assumed billion candidates cd9 cdkn1a chimeric computational discovered entities erg ets etv1 fusion fusions fusionseq harbor harboring ikbkb oncogene pigu predispose prone prostate reads rearrangement rearrangements seq tmprss2 transcriptome	achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi
Tagcloud (Difference) ?		assumed billion candidates cd9 cdkn1a chimeric computational discovered entities erg ets etv1 fusion fusions fusionseq harbor harboring ikbkb oncogene pigu predispose prone prostate reads rearrangement rearrangements seq tmprss2 transcriptome	achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi
Tagcloud (Intersection) ?