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ST3GAL3 and ACTG1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ST3GAL3
ACTG1
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
actin gamma 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Extracellular Region
Integral Component Of Golgi Membrane
Golgi Cisterna Membrane
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Plasma Membrane
Membrane
Myofibril
Filamentous Actin
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity
N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Biological Process
Carbohydrate Metabolic Process
Dolichol-linked Oligosaccharide Biosynthetic Process
Protein O-linked Glycosylation
Pathogenesis
O-glycan Processing
Keratan Sulfate Biosynthetic Process
Protein N-linked Glycosylation Via Asparagine
Glycosaminoglycan Metabolic Process
Keratan Sulfate Metabolic Process
Post-translational Protein Modification
Cellular Protein Metabolic Process
Small Molecule Metabolic Process
Sialylation
Retina Homeostasis
Movement Of Cell Or Subcellular Component
Axon Guidance
Cell Junction Assembly
Adherens Junction Organization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Sarcomere Organization
Cell-cell Junction Organization
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Membrane Organization
Platelet Aggregation
Pathways
Keratan sulfate/keratin metabolism
MPS I - Hurler syndrome
MPS IX - Natowicz syndrome
Glycosaminoglycan metabolism
Defective MGAT2 causes MGAT2-CDG (CDG-2a)
O-linked glycosylation
Defective CHST14 causes EDS, musculocontractural type
Myoclonic epilepsy of Lafora
MPS IIID - Sanfilippo syndrome D
Defective CHST6 causes MCDC1
Glycogen storage diseases
Defective ALG2 causes ALG2-CDG (CDG-1i)
Keratan sulfate biosynthesis
Diseases associated with glycosaminoglycan metabolism
Mucopolysaccharidoses
Defective ALG3 causes ALG3-CDG (CDG-1d)
Post-translational protein modification
Defective EXT2 causes exostoses 2
Signaling by NOTCH
Termination of O-glycan biosynthesis
Synthesis of substrates in N-glycan biosythesis
Asparagine N-linked glycosylation
MPS IV - Morquio syndrome A
Sialic acid metabolism
Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Metabolism of carbohydrates
O-linked glycosylation of mucins
Diseases associated with N-glycosylation of proteins
MPS VI - Maroteaux-Lamy syndrome
MPS IIIB - Sanfilippo syndrome B
Diseases of glycosylation
Defective B4GALT7 causes EDS, progeroid type
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Defective SLC26A2 causes chondrodysplasias
Defective ALG1 causes ALG1-CDG (CDG-1k)
Defective MOGS causes MOGS-CDG (CDG-2b)
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG9 causes ALG9-CDG (CDG-1l)
Defective PAPSS2 causes SEMD-PA
Defective MAN1B1 causes MRT15
MPS IIIA - Sanfilippo syndrome A
Pre-NOTCH Expression and Processing
Defective ALG11 causes ALG11-CDG (CDG-1p)
MPS IIIC - Sanfilippo syndrome C
Pre-NOTCH Processing in Golgi
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
MPS II - Hunter syndrome
Defective CHST3 causes SEDCJD
Defective B3GAT3 causes JDSSDHD
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Defective RFT1 causes RFT1-CDG (CDG-1n)
Defective ALG6 causes ALG6-CDG (CDG-1c)
Defective ALG8 causes ALG8-CDG (CDG-1h)
Defective ALG12 causes ALG12-CDG (CDG-1g)
Defective CHSY1 causes TPBS
MPS IV - Morquio syndrome B
MPS VII - Sly syndrome
Axon guidance
Gap junction degradation
Adherens junctions interactions
Translocation of GLUT4 to the plasma membrane
L1CAM interactions
Recycling pathway of L1
VEGFA-VEGFR2 Pathway
EPHB-mediated forward signaling
Interaction between L1 and Ankyrins
Cell-cell junction organization
EPH-ephrin mediated repulsion of cells
Gap junction trafficking and regulation
EPH-Ephrin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Cell junction organization
Formation of annular gap junctions
Gap junction trafficking
Signaling by VEGF
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Aging (time to event) (
21782286
)
Amyotrophic lateral sclerosis (age of onset) (
22959728
)
Protein-Protein Interactions
5 interactors:
ACTG1
RPL8
SCAMP2
TTR
ZBTB5
60 interactors:
ABLIM1
ACTB
ANXA5
APOE
ATF7IP
BCAP31
BRCA1
CAP1
CAP2
CAPZA3
CCDC22
CDKN2A
CFL1
CFL2
COTL1
CTBP2
CTTN
CYBB
DISC1
DNASE1
DSTN
DYNLL1
EHHADH
EIF6
FHOD1
FPR1
GIT2
GSN
GZMA
GZMK
LGALS13
LIG4
LSP1
MAP1A
MAPK6
MYO1A
MYOC
NDRG1
NR3C2
PFN2
PLD1
PLEC
PPP1R9A
PRSS23
PSEN2
PTPRO
RPS6KA5
SCIN
SH3GL2
ST3GAL3
SUMO4
TMSB4X
TMSB4Y
TNIK
VASP
VIL1
WASF1
WASL
WDYHV1
WIPF1
Entrez ID
6487
71
HPRD ID
05930
00017
Ensembl ID
ENSG00000126091
ENSG00000184009
Uniprot IDs
B4DX62
Q11203
P63261
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Cellular Component Organization
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Actin Cytoskeleton Organization
Positive Regulation Of Cytoskeleton Organization
Actin Polymerization Or Depolymerization
Regulation Of Cytoskeleton Organization
Actin Filament-based Process
Actin Filament Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Organelle Organization
Organelle Organization
Regulation Of Cellular Component Size
Chemotaxis
Cell Projection Organization
Neurogenesis
Negative Regulation Of Cytoskeleton Organization
Regulation Of Actin Filament Depolymerization
Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Polymerization
Negative Regulation Of Actin Filament Polymerization
Negative Regulation Of Protein Complex Assembly
Neuron Projection Development
Negative Regulation Of Protein Polymerization
Movement Of Cell Or Subcellular Component
Axon Guidance
Generation Of Neurons
Actin Filament Severing
Positive Regulation Of Cellular Component Biogenesis
Locomotion
Regulation Of Protein Depolymerization
Cell Development
Response To External Stimulus
Neuron Development
Nervous System Development
Axon Development
Regulation Of Protein Complex Disassembly
Regulation Of Cell Projection Organization
Actin Filament Depolymerization
Neuron Projection Morphogenesis
Axonogenesis
Neuron Differentiation
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Actin Filament Polymerization
Signal Transduction
Tagcloud
?
alteration
birc7
chrcc
chromophobe
cpq
distinctions
ectopic
enabled
exome
faah2
fusions
met
mitf
mutated
nccrccs
nf2
oncocytoma
oncocytomas
papillary
pdhb
pdxdc1
pnkd
prcc
rcc
slc5a3
transcriptome
trcc
unreported
znf765
Tagcloud (Difference)
?
alteration
birc7
chrcc
chromophobe
cpq
distinctions
ectopic
enabled
exome
faah2
fusions
met
mitf
mutated
nccrccs
nf2
oncocytoma
oncocytomas
papillary
pdhb
pdxdc1
pnkd
prcc
rcc
slc5a3
transcriptome
trcc
unreported
znf765
Tagcloud (Intersection)
?