ST3GAL3 and SCAMP2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ST3GAL3	SCAMP2
Gene Name		ST3 beta-galactoside alpha-2,3-sialyltransferase 3	secretory carrier membrane protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Extracellular Region Integral Component Of Golgi Membrane Golgi Cisterna Membrane	Nucleoplasm Golgi Apparatus Integral Component Of Membrane Transport Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Dolichol-linked Oligosaccharide Biosynthetic Process Protein O-linked Glycosylation Pathogenesis O-glycan Processing Keratan Sulfate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Glycosaminoglycan Metabolic Process Keratan Sulfate Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process Sialylation	Post-Golgi Vesicle-mediated Transport Protein Transport
Pathways		Keratan sulfate/keratin metabolism MPS I - Hurler syndrome MPS IX - Natowicz syndrome Glycosaminoglycan metabolism Defective MGAT2 causes MGAT2-CDG (CDG-2a) O-linked glycosylation Defective CHST14 causes EDS, musculocontractural type Myoclonic epilepsy of Lafora MPS IIID - Sanfilippo syndrome D Defective CHST6 causes MCDC1 Glycogen storage diseases Defective ALG2 causes ALG2-CDG (CDG-1i) Keratan sulfate biosynthesis Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective EXT2 causes exostoses 2 Signaling by NOTCH Termination of O-glycan biosynthesis Synthesis of substrates in N-glycan biosythesis Asparagine N-linked glycosylation MPS IV - Morquio syndrome A Sialic acid metabolism Defective MPDU1 causes MPDU1-CDG (CDG-1f) Metabolism of carbohydrates O-linked glycosylation of mucins Diseases associated with N-glycosylation of proteins MPS VI - Maroteaux-Lamy syndrome MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective SLC26A2 causes chondrodysplasias Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective PAPSS2 causes SEMD-PA Defective MAN1B1 causes MRT15 MPS IIIA - Sanfilippo syndrome A Pre-NOTCH Expression and Processing Defective ALG11 causes ALG11-CDG (CDG-1p) MPS IIIC - Sanfilippo syndrome C Pre-NOTCH Processing in Golgi Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 MPS II - Hunter syndrome Defective CHST3 causes SEDCJD Defective B3GAT3 causes JDSSDHD Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG12 causes ALG12-CDG (CDG-1g) Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome
Drugs
Diseases
GWAS		Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728)	Caffeine consumption ( 21490707)
Protein-Protein Interactions		5 interactors: ACTG1 RPL8 SCAMP2 TTR ZBTB5	5 interactors: ARIH2 SCAMP1 SLC9A7 SNAP23 ST3GAL3
Entrez ID		6487	10066
HPRD ID		05930	06073
Ensembl ID		ENSG00000126091
Uniprot IDs		B4DX62 Q11203	O15127
PDB IDs
Enriched GO Terms of Interacting Partners?			Post-Golgi Vesicle-mediated Transport
Tagcloud ?			abscission actin analyse bridge characterize connecting coordinated cytokinesis cytoskeleton daughter deliver endosome endosomes escrt escrts final fip3 framework icb ingression intercellular mediating narrows p50rhogap recycling scission severing spatiotemporal telophase
Tagcloud (Difference) ?			abscission actin analyse bridge characterize connecting coordinated cytokinesis cytoskeleton daughter deliver endosome endosomes escrt escrts final fip3 framework icb ingression intercellular mediating narrows p50rhogap recycling scission severing spatiotemporal telophase
Tagcloud (Intersection) ?