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POLR1E and POLR1B
Number of citations of the paper that reports this interaction (PMID
9254723
)
18
Data Source:
HPRD
(in vitro)
POLR1E
POLR1B
Gene Name
polymerase (RNA) I polypeptide E, 53kDa
polymerase (RNA) I polypeptide B, 128kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
DNA-directed RNA Polymerase I Complex
Nucleoplasm
Nucleolus
DNA-directed RNA Polymerase I Complex
Cytoplasm
Molecular Function
RNA Polymerase I Activity
RNA Polymerase I Transcription Factor Binding
DNA Binding
RNA Polymerase I Activity
DNA Binding
Protein Binding
Ribonucleoside Binding
Metal Ion Binding
Biological Process
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
RRNA Transcription
Gene Expression
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Embryo Implantation
RRNA Transcription
Gene Expression
Nucleologenesis
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Pathways
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
CD3EAP
NFKBIB
POLR1A
POLR1B
POLR1C
TAF1C
UBTF
14 interactors:
AKT2
CCND1
EIF3L
ESR1
GIT2
HDAC6
LDB1
LZTR1
MED20
NFKBIB
POLR1E
RPL37
RRN3
ZNF207
Entrez ID
64425
84172
HPRD ID
15096
06852
Ensembl ID
ENSG00000137054
ENSG00000125630
Uniprot IDs
Q9GZS1
Q9H9Y6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Elongation
Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Initiation
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RRNA Transcription
Biosynthetic Process
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Type I Interferon Production
Nucleologenesis
Regulation Of Metabolic Process
Regulation Of Type I Interferon Production
Nucleolus Organization
Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase I Promoter
Positive Regulation Of Cytokine Production
Chromatin Silencing At RDNA
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
Regulation Of Transcription From RNA Polymerase I Promoter
Regulation Of Cytokine Production
Chromatin Silencing
Transcription From RNA Polymerase III Promoter
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Innate Immune Response
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
RNA Biosynthetic Process
Gene Expression
Regulation Of Metabolic Process
Biosynthetic Process
DNA-templated Transcription, Initiation
Transcription, DNA-templated
RNA Metabolic Process
Mammary Gland Epithelium Development
Mammary Gland Epithelial Cell Proliferation
Transcription Initiation From RNA Polymerase I Promoter
Mammary Gland Development
Transcription From RNA Polymerase I Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Chromosome Organization
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Mammary Gland Lobule Development
Mammary Gland Alveolus Development
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Chromatin Organization
Histone H3-K4 Acetylation
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Hsp90 Deacetylation
Negative Regulation Of Gene Expression
Regulation Of Protein Metabolic Process
Regulation Of Oxidoreductase Activity
Positive Regulation Of Type I Interferon Production
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Positive Regulation Of Hemoglobin Biosynthetic Process
Polyubiquitinated Misfolded Protein Transport
Epithelial Cell Proliferation
Regulation Of Cell Cycle Arrest
Positive Regulation Of Metabolic Process
Re-entry Into Mitotic Cell Cycle
Prostate Epithelial Cord Elongation
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Cellular Response To Topologically Incorrect Protein
Regulation Of Type I Interferon Production
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Tagcloud (Intersection)
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