POLR1E and TAF1C

Number of citations of the paper that reports this interaction (PMID 15226435)
10

Data Source:
HPRD (in vitro)

		POLR1E	TAF1C
Gene Name		polymerase (RNA) I polypeptide E, 53kDa	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus DNA-directed RNA Polymerase I Complex	Nucleoplasm
	Molecular Function	RNA Polymerase I Activity RNA Polymerase I Transcription Factor Binding DNA Binding	DNA Binding Protein Binding
	Biological Process	RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS			Autism ( 22843504) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		7 interactors: CD3EAP NFKBIB POLR1A POLR1B POLR1C TAF1C UBTF	14 interactors: H2AFX POLR1E RRN3 SMN1 TAF1A TAF1B TAF1D TBP TK1 TP53 TRIM24 TTR UBTF UFD1L
Entrez ID		64425	9013
HPRD ID		15096	05364
Ensembl ID		ENSG00000137054	ENSG00000103168
Uniprot IDs		Q9GZS1	B3KUE8 Q15572
PDB IDs
Enriched GO Terms of Interacting Partners?		Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RRNA Transcription Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Type I Interferon Production Nucleologenesis Regulation Of Metabolic Process Regulation Of Type I Interferon Production Nucleolus Organization Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase I Promoter Positive Regulation Of Cytokine Production Chromatin Silencing At RDNA Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Cytokine Production Chromatin Silencing Transcription From RNA Polymerase III Promoter Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Innate Immune Response	Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Chromatin Silencing Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression RRNA Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Gene Silencing Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Biosynthetic Process Protein-DNA Complex Assembly Transcription From RNA Polymerase III Promoter Cellular Macromolecular Complex Assembly Cellular Component Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Fetal Process Involved In Parturition Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromitophagy Skeletal Muscle Cell Proliferation
Tagcloud ?			analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1b tata tbp tumourigenesis ubf
Tagcloud (Difference) ?			analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1b tata tbp tumourigenesis ubf
Tagcloud (Intersection) ?