Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
RFWD2 and SIPA1
Number of citations of the paper that reports this interaction (PMID
11461903
)
35
Data Source:
HPRD
(two hybrid, in vitro)
RFWD2
SIPA1
Gene Name
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
signal-induced proliferation-associated 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Focal Adhesion
Nuclear Speck
Nucleus
Nucleolus
Golgi Apparatus
Cytosol
Plasma Membrane
Transport Vesicle
Protein Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Activity
GTPase Activator Activity
Protein Binding
Protein C-terminus Binding
Rap GTPase Activator Activity
Biological Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Response To Ionizing Radiation
Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cytoskeleton Organization
Negative Regulation Of Cell Adhesion
Signal Transduction
Cell Proliferation
Negative Regulation Of Cell Growth
Positive Regulation Of Rap GTPase Activity
Intracellular Signal Transduction
Cellular Response To Water Deprivation
Positive Regulation Of GTPase Activity
Negative Regulation Of Cell Cycle
Pathways
p53-Dependent G1 DNA Damage Response
Autodegradation of the E3 ubiquitin ligase COP1
Stabilization of p53
Cell Cycle Checkpoints
p53-Dependent G1/S DNA damage checkpoint
G1/S DNA Damage Checkpoints
Rap1 signalling
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
CCT4
DET1
ETS1
ETS2
JUN
JUND
PTPN1
RB1CC1
SFN
SIPA1
TP53
UBE2D1
UBE2D2
YWHAZ
3 interactors:
CDKN1A
DVL1
RFWD2
Entrez ID
64326
6494
HPRD ID
07455
03713
Ensembl ID
ENSG00000143207
ENSG00000213445
Uniprot IDs
Q05CT6
Q8NHY2
F6RY50
Q96FS4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Response To Stress
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Release Of Cytochrome C From Mitochondria
Response To Abiotic Stimulus
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Response To Stress
Immune Response
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Transcription From RNA Polymerase II Promoter
Regulation Of DNA-templated Transcription In Response To Stress
Positive Regulation Of Mitochondrion Organization
Cellular Response To Extracellular Stimulus
Regulation Of Cell Cycle
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Apoptotic Mitochondrial Changes
Regulation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Response To Hypoxia
Regulation Of Mitochondrion Organization
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Hypoxia
Intracellular Signal Transduction
Cellular Response To Decreased Oxygen Levels
Response To Wounding
Regulation Of Cellular Component Organization
Toll-like Receptor Signaling Pathway
Apoptotic Signaling Pathway
Cellular Response To Oxygen Levels
Cellular Response To Stimulus
Mitochondrion Organization
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Immune System Process
Cellular Response To Starvation
Transforming Growth Factor Beta Receptor Signaling Pathway
Activation Of Innate Immune Response
Regulation Of Apoptotic Process
Organelle Organization
RNA Metabolic Process
Transcription, DNA-templated
Negative Regulation Of Cell Cycle
Negative Regulation Of Apoptotic Process
Regulation Of Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Response To Endoplasmic Reticulum Stress
Negative Regulation Of Programmed Cell Death
Response To Extracellular Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
DNA Damage Response, Signal Transduction By P53 Class Mediator
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Signal Transduction By P53 Class Mediator
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Response To Ionizing Radiation
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Protein Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Cell Cycle Checkpoint
Negative Regulation Of Kinase Activity
Convergent Extension Involved In Neural Plate Elongation
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Intracellular Signal Transduction
Negative Regulation Of Protein Phosphorylation
Collateral Sprouting
Intestinal Epithelial Cell Maturation
Regulation Of Cellular Protein Metabolic Process
Convergent Extension Involved In Organogenesis
Regulation Of Protein Catabolic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Phosphorylation
Tagcloud
?
1307t
allele
arms
chi
confer
conferred
ecm
extra
genotype
genotyping
hyderabad
insilco
institute
know
modifier
modulates
nizam
online
polymorphism
processing1
reconfirmed
rrp1b
rrp1b1307
rrp1b1307tt
rs9306160
rural
sciences
tt
urban
Tagcloud (Difference)
?
1307t
allele
arms
chi
confer
conferred
ecm
extra
genotype
genotyping
hyderabad
insilco
institute
know
modifier
modulates
nizam
online
polymorphism
processing1
reconfirmed
rrp1b
rrp1b1307
rrp1b1307tt
rs9306160
rural
sciences
tt
urban
Tagcloud (Intersection)
?