KIF13A and AP1M1

Number of citations of the paper that reports this interaction (PMID 11106728)
57

Data Source:
BioGRID (pull down)

		KIF13A	AP1M1
Gene Name		kinesin family member 13A	adaptor-related protein complex 1, mu 1 subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Centrosome Kinesin Complex Microtubule Endosome Membrane Midbody Trans-Golgi Network Membrane	Golgi Membrane Lysosomal Membrane Cytosol Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Extracellular Vesicular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Protein Binding
	Biological Process	Cytokinesis Intracellular Protein Transport Microtubule-based Movement Metabolic Process Endosome To Lysosome Transport Melanosome Organization Cargo Loading Into Vesicle Golgi To Plasma Membrane Protein Transport Plus-end-directed Vesicle Transport Along Microtubule	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS		Height ( 18391951) Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		7 interactors: AP1B1 AP1G1 AP1M1 ATF7IP GTF2H1 PIH1D3 PPP1CA	43 interactors: AP1B1 AP1M2 AP2B1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SDCCAG3 SELP SSX2IP TGOLN2 TIFA TNIP1 VAMP4 ZBTB14 ZBTB43 ZBTB44 ZBTB8A
Entrez ID		63971	8907
HPRD ID		09256	04639
Ensembl ID		ENSG00000137177	ENSG00000072958
Uniprot IDs		Q9H1H9	B3KNH5 E7ENJ6 Q59EK3 Q9BXS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Viral Process Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Pigment Granule Maturation Endosome To Melanosome Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cellular Pigment Accumulation Melanosome Organization Pigment Granule Organization Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Antigen Processing And Presentation Cellular Pigmentation Developmental Pigmentation Pigmentation Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Membrane Organization Endosomal Transport Vesicle Organization Regulation Of Gene Expression, Epigenetic Intracellular Protein Transport Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Golgi To Vacuole Transport Regulation Of Glycogen Catabolic Process Axonemal Dynein Complex Assembly Regulation Of Immune System Process Cellular Protein Localization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Nucleotide-excision Repair, DNA Damage Removal Protein Transport Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Triglyceride Catabolic Process Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of DNA-templated Transcription, Initiation Entrainment Of Circadian Clock By Photoperiod Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Intracellular Transport Positive Regulation Of Natural Killer Cell Activation Termination Of RNA Polymerase I Transcription Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Transcription Elongation From RNA Polymerase I Promoter	Vesicle-mediated Transport Cellular Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Regulation Of Defense Response To Virus By Virus Intracellular Transport Endosomal Transport Protein Localization Lysosomal Transport Golgi Vesicle Transport Regulation Of Immune System Process Cellular Protein Localization Vacuolar Transport Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Microtubule Cytoskeleton Organization Endomembrane System Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Transport Regulation Of Cellular Process Startle Response Microtubule-based Process Endosome To Lysosome Transport Positive Regulation Of Cell Activation Cytoskeleton Organization Clathrin-mediated Endocytosis Establishment Of Protein Localization Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Membrane Organization Cellular Protein Complex Assembly Organelle Organization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Histone H3-K9 Acetylation Intrahepatic Bile Duct Development Positive Regulation Of Natural Killer Cell Degranulation Selenium Compound Metabolic Process Cytoplasmic Transport Glutamate Receptor Signaling Pathway Convergent Extension Involved In Neural Plate Elongation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Golgi To Lysosome Transport Neuron-neuron Synaptic Transmission
Tagcloud ?		adaptin adaptor ap associates blockade cargo cargoes contained directed end kifs kinesin m6pr mannnose microtubule mislocalization motor phosphate plus remains respective subunit superfamily targets tgn transport transports unclear vesicles	19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic
Tagcloud (Difference) ?		adaptin ap associates blockade cargo cargoes contained directed end kifs kinesin m6pr mannnose microtubule mislocalization motor phosphate plus remains respective subunit superfamily targets tgn transport transports unclear vesicles	19p13 ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic
Tagcloud (Intersection) ?		adaptor