KIF13A and AP1B1

Number of citations of the paper that reports this interaction (PMID 11106728)
57

Data Source:
HPRD (in vitro, in vivo)

		KIF13A	AP1B1
Gene Name		kinesin family member 13A	adaptor-related protein complex 1, beta 1 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Centrosome Kinesin Complex Microtubule Endosome Membrane Midbody Trans-Golgi Network Membrane	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Transporter Activity Protein Binding Protein Transporter Activity Protein Kinase Binding
	Biological Process	Cytokinesis Intracellular Protein Transport Microtubule-based Movement Metabolic Process Endosome To Lysosome Transport Melanosome Organization Cargo Loading Into Vesicle Golgi To Plasma Membrane Protein Transport Plus-end-directed Vesicle Transport Along Microtubule	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS		Height ( 18391951) Prostate cancer (gene x gene interaction) ( 22219177)	Carotid atherosclerosis in HIV infection ( 20009918)
Protein-Protein Interactions		7 interactors: AP1B1 AP1G1 AP1M1 ATF7IP GTF2H1 PIH1D3 PPP1CA	22 interactors: AMPH AP1G1 AP1M1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP KIF13A NTRK2 PIP5K1C PRKDC SHBG SMAD2
Entrez ID		63971	162
HPRD ID		09256	02541
Ensembl ID		ENSG00000137177	ENSG00000100280
Uniprot IDs		Q9H1H9	Q10567
PDB IDs			4HMY
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Viral Process Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Pigment Granule Maturation Endosome To Melanosome Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cellular Pigment Accumulation Melanosome Organization Pigment Granule Organization Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Antigen Processing And Presentation Cellular Pigmentation Developmental Pigmentation Pigmentation Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Membrane Organization Endosomal Transport Vesicle Organization Regulation Of Gene Expression, Epigenetic Intracellular Protein Transport Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Golgi To Vacuole Transport Regulation Of Glycogen Catabolic Process Axonemal Dynein Complex Assembly Regulation Of Immune System Process Cellular Protein Localization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Nucleotide-excision Repair, DNA Damage Removal Protein Transport Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Triglyceride Catabolic Process Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of DNA-templated Transcription, Initiation Entrainment Of Circadian Clock By Photoperiod Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Intracellular Transport Positive Regulation Of Natural Killer Cell Activation Termination Of RNA Polymerase I Transcription Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Transcription Elongation From RNA Polymerase I Promoter	Post-Golgi Vesicle-mediated Transport Regulation Of Defense Response To Virus By Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Protein Localization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Organelle Organization Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Cellular Localization Viral Process Regulation Of Defense Response To Virus Establishment Of Vesicle Localization Melanosome Organization Pigment Granule Organization Vesicle Localization Cell Cycle Cell Cycle Checkpoint Antigen Processing And Presentation Of Peptide Antigen Cell Cycle Process Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Establishment Of Localization In Cell Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Antigen Processing And Presentation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Chromosome Segregation Negative Regulation Of Mitotic Cell Cycle Phase Transition Establishment Of Organelle Localization Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Cell Differentiation Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Checkpoint Negative Regulation Of Proteolysis Cellular Protein Localization Response To Gamma Radiation Negative Regulation Of Protein Processing Cellular Pigmentation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Temperature Stimulus Endosome To Melanosome Transport Pigment Granule Maturation Regulation Of Protein Processing Negative Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		adaptin adaptor ap associates blockade cargo cargoes contained directed end kifs kinesin m6pr mannnose microtubule mislocalization motor phosphate plus remains respective subunit superfamily targets tgn transport transports unclear vesicles
Tagcloud (Difference) ?		adaptin adaptor ap associates blockade cargo cargoes contained directed end kifs kinesin m6pr mannnose microtubule mislocalization motor phosphate plus remains respective subunit superfamily targets tgn transport transports unclear vesicles
Tagcloud (Intersection) ?