KIF13A and AP1B1

Number of citations of the paper that reports this interaction (PubMedID 11106728)
0

Data Source:
HPRD (in vitro, in vivo)

		KIF13A	AP1B1
Description		kinesin family member 13A	adaptor related protein complex 1 subunit beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endosome Golgi Apparatus Centrosome Cytoskeleton Kinesin Complex Microtubule Endosome Membrane Membrane Midbody Trans-Golgi Network Membrane	Golgi Membrane Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Synaptic Vesicle Endomembrane System Membrane Membrane Coat AP-1 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity	Protein Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Microtubule-based Movement Endosome To Lysosome Transport Protein Transport Melanosome Organization Regulation Of Cytokinesis Vesicle Cargo Loading Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization Cell Division Plus-end-directed Vesicle Transport Along Microtubule	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Protein Transport Vesicle-mediated Transport Platelet Dense Granule Organization Basolateral Protein Secretion Melanosome Assembly
Pathways		Association of TriC/CCT with target proteins during biosynthesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Height ( 18391951) Intrinsic epigenetic age acceleration ( 29374233)	Aspartate aminotransferase levels ( 33547301) Carotid atherosclerosis in HIV infection ( 20009918) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 28869591 30598549) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		9 interacting genes: AP1B1 AP1G1 AP1M1 ATF7IP DNAAF6 GTF2H1 PPP1CA TRIM55 USP7	45 interacting genes: - AGR3 AP1G1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CEBPA CLTC CREBBP CRYBB1 FARS2 FILNC1 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PIP5K1C PLK2 POM121 PRKDC PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TSGA10IP U2AF1
Entrez ID		63971	162
HPRD ID		09256	02541
Ensembl ID		ENSG00000137177	ENSG00000100280
Uniprot IDs		Q9H1H9	Q10567
PDB IDs			4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF 7R4H 7UX3 8D4C 8D4D 8D4E 8D4F 8D4G 8D9R 8D9S 8D9T 8D9U 8D9V 8D9W
Enriched GO Terms of Interacting Partners?		AP-1 Adaptor Complex Melanosome Assembly Platelet Dense Granule Organization Melanosome Organization Clathrin-coated Vesicle Membrane Pigment Granule Organization Basolateral Protein Secretion Secretory Granule Organization Endosome To Melanosome Transport Clathrin Adaptor Complex Trans-Golgi Network Membrane Clathrin Adaptor Activity Cytoplasmic Vesicle Membrane Membrane Coat Nucleotide-excision Repair Organelle Assembly Vesicle Organization Early Endosome Clathrin-coated Vesicle Lysosomal Membrane Synaptic Vesicle Budding From Endosome RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of Glucose Metabolic Process Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Symbiont-mediated Disruption Of Host Cell PML Body Protein Localization To Extracellular Region Protein Secretion Establishment Of Protein Localization To Extracellular Region Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Regulation Of Circadian Rhythm Positive Regulation Of Natural Killer Cell Degranulation DNA Repair Intracellular Protein Transport Glycogen Granule Regulation Of Establishment Of Protein Localization To Telomere PTW/PP1 Phosphatase Complex Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Interleukin-4 Production Diapedesis Negative Regulation Of Gene Expression, Epigenetic RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process	Histone H2AXS139 Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Presynaptic Endocytosis Establishment Of RNA Localization To Telomere Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomerase Catalytic Core Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Cellular Response To Heat Intracellular Protein Localization Regulation Of Cell Cycle Clathrin Adaptor Activity Negative Regulation Of Cell Cycle Process Establishment Of Protein Localization DNA-dependent Protein Kinase Activity Intracellular Protein Transport Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Cell Cycle Phase Transition Clathrin-coated Pit Protein Transport Basolateral Protein Secretion Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Mitotic Cell Cycle Clathrin-coated Vesicle Membrane Vesicle-mediated Transport In Synapse MutSalpha Complex Binding Homologous Recombination Synaptic Vesicle Endocytosis Negative Regulation Of Mitotic Nuclear Division Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Telomere Localization Protein Localization To Chromosome Somatic Cell DNA Recombination Trans-Golgi Network Membrane Endocytosis Somitogenesis Meiotic Sister Chromatid Cohesion Male Meiotic Nuclear Division Nucleotide Binding Regulation Of Receptor-mediated Endocytosis Segmentation Response To Gamma Radiation Mitotic G2/M Transition Checkpoint
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