STX1A and SNAP29

Number of citations of the paper that reports this interaction (PMID 9852078)
37

Data Source:
HPRD (two hybrid, in vitro)

		STX1A	SNAP29
Gene Name		syntaxin 1A (brain)	synaptosomal-associated protein, 29kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane SNARE Complex Actomyosin Neuron Projection Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex	Cytoplasm Centrosome Plasma Membrane Cell Junction SNARE Complex Neuron Projection Synapse
	Molecular Function	SNARE Binding Glycoprotein Binding SNAP Receptor Activity Protein Binding Myosin Binding Calcium Channel Inhibitor Activity Chloride Channel Inhibitor Activity Kinase Binding Protein Domain Specific Binding Protein Binding, Bridging Myosin Head/neck Binding ATP-dependent Protein Binding Protein Heterodimerization Activity Protein N-terminus Binding Calcium-dependent Protein Binding	SNAP Receptor Activity Syntaxin Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Energy Reserve Metabolic Process Intracellular Protein Transport Synaptic Transmission Neurotransmitter Secretion Pathogenesis Response To Gravity Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Calcium Ion-dependent Exocytosis Synaptic Vesicle Fusion To Presynaptic Membrane Secretion By Cell Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Exocytosis Vesicle Docking Regulation Of Insulin Secretion Positive Regulation Of Excitatory Postsynaptic Membrane Potential	Autophagic Vacuole Fusion Exocytosis Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Fusion
Pathways		Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Toxicity of botulinum toxin type C (BoNT/C) Norepinephrine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Peptide hormone metabolism Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Insulin processing Serotonin Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: ABCC9 APBA1 ATP4B ATP6V1B1 CACNA1D CCSER2 CDK5 CFTR CPLX1 CSNK2A1 CSNK2A2 DAPK1 KCNB1 NAPA NAPB NSF PSMA3 RAB27A RIMS1 SCNN1A SCNN1B SCNN1G SDCBP SEPT2 SEPT5 SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A9 SNAP23 SNAP25 SNAP29 SNPH STX8 STXBP1 STXBP2 STXBP5 STXBP6 SUMO1P1 SYT1 SYT4 SYT7 SYTL4 TRDMT1 TXLNA TXLNB UNC13B VAMP1 VAMP2 VAMP5 VAMP7 VAMP8 VAPB VIM VPS11 VPS18	22 interactors: AP2A1 ATF4 CD7 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 RASSF7 STX12 STX17 STX1A STX3 STX4 STX6 STX7 VAMP1 VAMP2 VAMP4 VAMP5 VAMP7
Entrez ID		6804	9342
HPRD ID		01721	11968
Ensembl ID		ENSG00000106089	ENSG00000099940
Uniprot IDs		A8MZ54 Q16623 Q75ME0	O95721
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis Secretion By Cell Neurotransmitter Transport Secretion Regulation Of Exocytosis Regulation Of Neurotransmitter Levels Transport Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Transmission Cell-cell Signaling Regulation Of Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Cellular Localization Positive Regulation Of Exocytosis Regulation Of Cellular Localization Membrane Fusion Glutamate Secretion Establishment Of Vesicle Localization Vesicle Localization Ion Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Amino Acid Transport Vesicle Docking Organelle Fusion Membrane Docking Establishment Of Organelle Localization Membrane Organization Acid Secretion Vesicle Organization Positive Regulation Of Secretion Organelle Localization Protein Localization Monovalent Inorganic Cation Transport Anion Transport Dicarboxylic Acid Transport Regulated Secretory Pathway Metal Ion Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transport Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Sodium Ion Transport Organic Anion Transport	Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Vesicle-mediated Transport Membrane Organization Intracellular Protein Transport Establishment Of Localization In Cell Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Vesicle Docking SNARE Complex Assembly Membrane Docking Exocytosis Protein Localization Endomembrane System Organization Golgi Vesicle Transport Secretion By Cell Post-Golgi Vesicle-mediated Transport Organelle Organization Neurotransmitter Secretion Secretion Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Neurotransmitter Levels Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis Regulation Of Protein Localization Neurotransmitter Transport Golgi Organization Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Plasma Membrane Endosomal Transport Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Localization Eosinophil Degranulation Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Golgi To Plasma Membrane Transport Calcium Ion-dependent Exocytosis Protein Localization To Plasma Membrane Regulation Of Exocytosis Long-term Synaptic Potentiation Golgi Ribbon Formation Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface Positive Regulation Of Exocytosis
Tagcloud ?		colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence	92e accumulates architecture asparagine autophagic autophagosomes cednik dispensable distinctive dysgenesis highlighting hop hopscotch ichthyosis keratoderma localizes neuropathy npf nsf organelles palmoplantar phenylalanine routes snare stat92e synaptosomal trafficking uncharacterized unlikely
Tagcloud (Difference) ?		colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence	92e accumulates architecture asparagine autophagic autophagosomes cednik dispensable distinctive dysgenesis highlighting hop hopscotch ichthyosis keratoderma localizes neuropathy npf nsf organelles palmoplantar phenylalanine routes snare stat92e synaptosomal trafficking uncharacterized unlikely
Tagcloud (Intersection) ?