MEP1B and OS9

Number of citations of the paper that reports this interaction (PMID 12093806)
10

Data Source:
HPRD (two hybrid, in vitro)

		MEP1B	OS9
Gene Name		meprin A, beta	osteosarcoma amplified 9, endoplasmic reticulum lectin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding	Glycoprotein Binding Protease Binding Protein Binding Carbohydrate Binding
	Biological Process	Proteolysis Inflammatory Response Digestion Toxin Transport	Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination ER-associated Ubiquitin-dependent Protein Catabolic Process Response To Endoplasmic Reticulum Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways			Hedgehog ligand biogenesis Processing-defective Hh variants abrogate ligand secretion Hh ligand biogenesis disease Signaling by Hedgehog
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT	16 interactors: ACVR1B CPNE6 CREB3 DCSTAMP EGLN1 EGLN3 EIF6 FOXM1 HIF1A MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B
Entrez ID		4225	10956
HPRD ID		02667	17804
Ensembl ID		ENSG00000141434	ENSG00000135506
Uniprot IDs		J3QKX5 Q16820	B4E321 Q13438
PDB IDs		4GWM 4GWN	3AIH
Enriched GO Terms of Interacting Partners?		Feeding Behavior Regulation Of Appetite Digestion G-protein Coupled Receptor Signaling Pathway Behavior Negative Regulation Of Glial Cell Apoptotic Process Neuropeptide Signaling Pathway Regulation Of Platelet Aggregation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Response To Food Response To Nutrient Levels Regulation Of Protein Binding Response To Extracellular Stimulus Response To Stimulus Regulation Of Cellular Ketone Metabolic Process Regulation Of Platelet Activation Eating Behavior Platelet Activation Response To External Stimulus Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Body Fluid Levels Negative Regulation Of Insulin Receptor Signaling Pathway Cellular Response To Glucagon Stimulus Positive Regulation Of Protein Metabolic Process Peptidyl-threonine Phosphorylation Regulation Of Binding Activation Of Phospholipase C Activity Cell Proliferation Response To Glucagon Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Insulin Receptor Signaling Pathway Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Cell Death Apoptotic Signaling Pathway Positive Regulation Of Phospholipase Activity Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Protein Modification Process Negative Regulation Of MAP Kinase Activity Negative Regulation Of Apoptotic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Oxygen Levels Cellular Response To Stress Oxygen Homeostasis Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Myeloid Cell Differentiation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Regulation Of Growth Nodal Signaling Pathway Regulation Of Cell Growth Positive Regulation Of Erythrocyte Differentiation 4-hydroxyproline Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Activin Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Stress Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Peptidyl-proline Hydroxylation Protein Hydroxylation Activin Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Myeloid Cell Differentiation Heterocycle Metabolic Process Regulation Of Erythrocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus In Utero Embryonic Development Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Growth Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Cellular Macromolecular Complex Assembly Cellular Response To Stimulus Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Cortical Microtubule Organization Osmosensory Signaling Pathway Neural Fold Elevation Formation Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		angptl2 cldn10 cldn4 cst6 dioestrus enpp1 epas1 itgb4 lgals1 lgals3bp maged1 metoestrus muc16 oestrogens oestrous oestrus pcsk5 plat preoestrus sepp1 simmental slc11a2 slc16a1 slc1a1 tdgf1 tek timp1 timp2 tjp1	branch c57y calnexin calreticulin cnx constrained erad folded folding futile glc1man7glcnac2 glycan glycans glycoproteins harbours improperly interconnected kifunensine lectins mannosidases mns4 mns5 oligosaccharide sel1l sort stabilized strubbelig subex thaliana
Tagcloud (Difference) ?		angptl2 cldn10 cldn4 cst6 dioestrus enpp1 epas1 itgb4 lgals1 lgals3bp maged1 metoestrus muc16 oestrogens oestrous oestrus pcsk5 plat preoestrus sepp1 simmental slc11a2 slc16a1 slc1a1 tdgf1 tek timp1 timp2 tjp1	branch c57y calnexin calreticulin cnx constrained erad folded folding futile glc1man7glcnac2 glycan glycans glycoproteins harbours improperly interconnected kifunensine lectins mannosidases mns4 mns5 oligosaccharide sel1l sort stabilized strubbelig subex thaliana
Tagcloud (Intersection) ?