SCP2 and PITPNA

Number of citations of the paper that reports this interaction (PMID 15182174)
11

Data Source:
BioGRID (fluorescent resonance energy transfer)

		SCP2	PITPNA
Gene Name		sterol carrier protein 2	phosphatidylinositol transfer protein, alpha
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Peroxisome Peroxisomal Matrix Membrane Intracellular Membrane-bounded Organelle Protein Complex Extracellular Vesicular Exosome	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Fatty-acyl-CoA Binding Receptor Binding Protein Binding Phosphatidylinositol Transporter Activity Cholesterol Binding Propanoyl-CoA C-acyltransferase Activity Long-chain Fatty Acyl-CoA Binding Oleic Acid Binding	Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transporter Activity
	Biological Process	Steroid Biosynthetic Process Bile Acid Biosynthetic Process Progesterone Biosynthetic Process Lipid Transport Peroxisome Organization Bile Acid Metabolic Process Phospholipid Transport Positive Regulation Of Intracellular Cholesterol Transport Inositol Trisphosphate Biosynthetic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Steroid Metabolic Process Protein Localization To Plasma Membrane Lipid Hydroperoxide Transport	Lipid Metabolic Process Axon Guidance Visual Perception Phospholipid Transport
Pathways		Metabolism of lipids and lipoproteins alpha-linolenic acid (ALA) metabolism alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	Axon guidance Role of second messengers in netrin-1 signaling Netrin-1 signaling
Drugs			1,2-Diacyl-Sn-Glycero-3-Phosphoinositol (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ACAA2 ACOX1 CACNA1A CAV1 EHHADH PEX5 PITPNA TRIP13	8 interactors: CSNK2B DCC EGFR NEO1 PI4KA PIK3C3 PLCG1 SCP2
Entrez ID		6342	5306
HPRD ID		01700	02548
Ensembl ID		ENSG00000116171	ENSG00000174238
Uniprot IDs		B2R761 E9PLD1 P22307 Q59HG9	B4E1U1 Q00169
PDB IDs		1QND 2C0L	1UW5
Enriched GO Terms of Interacting Partners?		Fatty Acid Beta-oxidation Lipid Metabolic Process Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Fatty Acid Metabolic Process Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Cellular Lipid Catabolic Process Organic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Small Molecule Metabolic Process Lipid Modification Carboxylic Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Peroxisome Organization Membrane Organization Mitochondrial Membrane Organization Protein Localization To Membrane Cerebellar Molecular Layer Development Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Oxygen Levels Lipid Homeostasis Membrane Depolarization Vestibular Nucleus Development Negative Regulation Of Protein Homotetramerization Nitric Oxide Homeostasis Neuromuscular Process Oxidation-reduction Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Protein Import Into Peroxisome Matrix, Translocation Regulation Of Inward Rectifier Potassium Channel Activity Positive Regulation Of Cholesterol Homeostasis Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Gamma-aminobutyric Acid Secretion Negative Regulation Of Pinocytosis Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Mammary Gland Involution Organelle Organization Cytosolic Calcium Ion Homeostasis	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Phosphorylation Cell Part Morphogenesis Response To External Stimulus Neuron Development Cellular Lipid Metabolic Process Cell Morphogenesis Phosphatidylinositol-mediated Signaling Neuron Differentiation Cell Projection Organization Locomotion Lipid Metabolic Process Regulation Of Phosphorylation Anatomical Structure Morphogenesis Cellular Response To Epidermal Growth Factor Stimulus Lipid Modification Response To Organic Substance Response To Epidermal Growth Factor Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Protein Phosphorylation Positive Regulation Of Intracellular Transport Regulation Of Protein Kinase Activity Generation Of Neurons Phosphate-containing Compound Metabolic Process Regulation Of Kinase Activity Neurogenesis Regulation Of Blood Vessel Endothelial Cell Migration Cell Development Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Protein Modification Process Cellular Response To Organic Substance Positive Regulation Of Phospholipase C Activity Signal Transduction Activation Of MAPKK Activity Phospholipid Metabolic Process Organophosphate Metabolic Process Response To Stimulus Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Signaling
Tagcloud ?		cannabinoid cannabinoids cb chemotactic chemotaxis clone confocal crosstalk cxcl12 cxcr4 cytoskeletal elucidation healing innovative jwh mcf7 metastasis mmtv modulate nt orthotopic p42 p44 possess psychoactive pymt syngenic tumorigenic wound
Tagcloud (Difference) ?		cannabinoid cannabinoids cb chemotactic chemotaxis clone confocal crosstalk cxcl12 cxcr4 cytoskeletal elucidation healing innovative jwh mcf7 metastasis mmtv modulate nt orthotopic p42 p44 possess psychoactive pymt syngenic tumorigenic wound
Tagcloud (Intersection) ?