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PITPNA and PI4KA
Number of citations of the paper that reports this interaction (PMID
7761838
)
28
Data Source:
HPRD
(in vivo)
PITPNA
PI4KA
Gene Name
phosphatidylinositol transfer protein, alpha
phosphatidylinositol 4-kinase, catalytic, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Extracellular Vesicular Exosome
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Golgi-associated Vesicle Membrane
Extracellular Vesicular Exosome
Molecular Function
Lipid Binding
Phosphatidylcholine Transporter Activity
Phosphatidylinositol Transporter Activity
1-phosphatidylinositol 4-kinase Activity
Protein Binding
ATP Binding
Biological Process
Lipid Metabolic Process
Axon Guidance
Visual Perception
Phospholipid Transport
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Signal Transduction
Small Molecule Metabolic Process
Phosphatidylinositol Phosphorylation
Phosphatidylinositol-mediated Signaling
Pathways
Axon guidance
Role of second messengers in netrin-1 signaling
Netrin-1 signaling
Synthesis of PIPs at the Golgi membrane
Metabolism of lipids and lipoproteins
Synthesis of PIPs at the ER membrane
Phospholipid metabolism
PI Metabolism
Drugs
1,2-Diacyl-Sn-Glycero-3-Phosphoinositol
(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
CSNK2B
DCC
EGFR
NEO1
PI4KA
PIK3C3
PLCG1
SCP2
9 interactors:
C8orf33
CD4
CD7
LCK
MRPL44
MTNR1B
PITPNA
STRN4
TNNT1
Entrez ID
5306
5297
HPRD ID
02548
08972
Ensembl ID
ENSG00000174238
ENSG00000241973
Uniprot IDs
B4E1U1
Q00169
B4DYG5
J3KN10
P42356
Q4LE69
PDB IDs
1UW5
Enriched GO Terms of Interacting Partners
?
Axon Guidance
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Cell Projection Morphogenesis
Positive Regulation Of Phosphorylation
Cell Part Morphogenesis
Response To External Stimulus
Neuron Development
Cellular Lipid Metabolic Process
Cell Morphogenesis
Phosphatidylinositol-mediated Signaling
Neuron Differentiation
Cell Projection Organization
Locomotion
Lipid Metabolic Process
Regulation Of Phosphorylation
Anatomical Structure Morphogenesis
Cellular Response To Epidermal Growth Factor Stimulus
Lipid Modification
Response To Organic Substance
Response To Epidermal Growth Factor
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Intracellular Transport
Regulation Of Protein Kinase Activity
Generation Of Neurons
Phosphate-containing Compound Metabolic Process
Regulation Of Kinase Activity
Neurogenesis
Regulation Of Blood Vessel Endothelial Cell Migration
Cell Development
Inositol Phosphate Metabolic Process
Activation Of Phospholipase C Activity
Positive Regulation Of Protein Modification Process
Cellular Response To Organic Substance
Positive Regulation Of Phospholipase C Activity
Signal Transduction
Activation Of MAPKK Activity
Phospholipid Metabolic Process
Organophosphate Metabolic Process
Response To Stimulus
Regulation Of Cellular Localization
Regulation Of Protein Phosphorylation
Signaling
Regulation Of Defense Response To Virus By Virus
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Leukocyte Aggregation
Leukocyte Cell-cell Adhesion
Homotypic Cell-cell Adhesion
Lymphocyte Activation
T Cell Costimulation
Regulation Of Defense Response To Virus
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Leukocyte Activation
Single Organismal Cell-cell Adhesion
T Cell Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Regulation Of Muscle Contraction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
T Cell Differentiation
Cell Activation
Positive Regulation Of T Cell Activation
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Homotypic Cell-cell Adhesion
Slow-twitch Skeletal Muscle Fiber Contraction
Enzyme Linked Receptor Protein Signaling Pathway
Lymphocyte Differentiation
Positive Regulation Of Gamma-delta T Cell Differentiation
Positive Regulation Of Cell-cell Adhesion
Positive Regulation Of Gamma-delta T Cell Activation
Positive Regulation Of Uterine Smooth Muscle Contraction
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Regulation Of Gamma-delta T Cell Differentiation
Modulation By Virus Of Host Process
Cellular Zinc Ion Homeostasis
Positive Regulation Of Interleukin-2 Biosynthetic Process
Leukocyte Differentiation
Zinc Ion Homeostasis
Cell Adhesion
Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
Positive Regulation Of T Cell Receptor Signaling Pathway
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Locomotion
Regulation Of Lymphocyte Activation
Regulation Of Cellular Amino Acid Metabolic Process
Immune Response
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