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PITPNA and SCP2
Number of citations of the paper that reports this interaction (PMID
15182174
)
11
Data Source:
BioGRID
(fluorescent resonance energy transfer)
PITPNA
SCP2
Gene Name
phosphatidylinositol transfer protein, alpha
sterol carrier protein 2
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Extracellular Vesicular Exosome
Nucleoplasm
Cytoplasm
Mitochondrion
Peroxisome
Peroxisomal Matrix
Membrane
Intracellular Membrane-bounded Organelle
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Lipid Binding
Phosphatidylcholine Transporter Activity
Phosphatidylinositol Transporter Activity
Fatty-acyl-CoA Binding
Receptor Binding
Protein Binding
Phosphatidylinositol Transporter Activity
Cholesterol Binding
Propanoyl-CoA C-acyltransferase Activity
Long-chain Fatty Acyl-CoA Binding
Oleic Acid Binding
Biological Process
Lipid Metabolic Process
Axon Guidance
Visual Perception
Phospholipid Transport
Steroid Biosynthetic Process
Bile Acid Biosynthetic Process
Progesterone Biosynthetic Process
Lipid Transport
Peroxisome Organization
Bile Acid Metabolic Process
Phospholipid Transport
Positive Regulation Of Intracellular Cholesterol Transport
Inositol Trisphosphate Biosynthetic Process
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Unsaturated Fatty Acid Metabolic Process
Alpha-linolenic Acid Metabolic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Positive Regulation Of Steroid Metabolic Process
Protein Localization To Plasma Membrane
Lipid Hydroperoxide Transport
Pathways
Axon guidance
Role of second messengers in netrin-1 signaling
Netrin-1 signaling
Metabolism of lipids and lipoproteins
alpha-linolenic acid (ALA) metabolism
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Drugs
1,2-Diacyl-Sn-Glycero-3-Phosphoinositol
(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
CSNK2B
DCC
EGFR
NEO1
PI4KA
PIK3C3
PLCG1
SCP2
8 interactors:
ACAA2
ACOX1
CACNA1A
CAV1
EHHADH
PEX5
PITPNA
TRIP13
Entrez ID
5306
6342
HPRD ID
02548
01700
Ensembl ID
ENSG00000174238
ENSG00000116171
Uniprot IDs
B4E1U1
Q00169
B2R761
E9PLD1
P22307
Q59HG9
PDB IDs
1UW5
1QND
2C0L
Enriched GO Terms of Interacting Partners
?
Axon Guidance
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Cell Projection Morphogenesis
Positive Regulation Of Phosphorylation
Cell Part Morphogenesis
Response To External Stimulus
Neuron Development
Cellular Lipid Metabolic Process
Cell Morphogenesis
Phosphatidylinositol-mediated Signaling
Neuron Differentiation
Cell Projection Organization
Locomotion
Lipid Metabolic Process
Regulation Of Phosphorylation
Anatomical Structure Morphogenesis
Cellular Response To Epidermal Growth Factor Stimulus
Lipid Modification
Response To Organic Substance
Response To Epidermal Growth Factor
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Intracellular Transport
Regulation Of Protein Kinase Activity
Generation Of Neurons
Phosphate-containing Compound Metabolic Process
Regulation Of Kinase Activity
Neurogenesis
Regulation Of Blood Vessel Endothelial Cell Migration
Cell Development
Inositol Phosphate Metabolic Process
Activation Of Phospholipase C Activity
Positive Regulation Of Protein Modification Process
Cellular Response To Organic Substance
Positive Regulation Of Phospholipase C Activity
Signal Transduction
Activation Of MAPKK Activity
Phospholipid Metabolic Process
Organophosphate Metabolic Process
Response To Stimulus
Regulation Of Cellular Localization
Regulation Of Protein Phosphorylation
Signaling
Fatty Acid Beta-oxidation
Lipid Metabolic Process
Fatty Acid Oxidation
Lipid Oxidation
Fatty Acid Catabolic Process
Fatty Acid Metabolic Process
Cellular Lipid Metabolic Process
Carboxylic Acid Metabolic Process
Cellular Lipid Catabolic Process
Organic Acid Metabolic Process
Monocarboxylic Acid Metabolic Process
Small Molecule Metabolic Process
Lipid Modification
Carboxylic Acid Catabolic Process
Very Long-chain Fatty Acid Metabolic Process
Lipid Catabolic Process
Peroxisome Organization
Membrane Organization
Mitochondrial Membrane Organization
Protein Localization To Membrane
Cerebellar Molecular Layer Development
Regulation Of Membrane Repolarization During Action Potential
Negative Regulation Of Peptidyl-tyrosine Autophosphorylation
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Cellular Response To Oxygen Levels
Lipid Homeostasis
Membrane Depolarization
Vestibular Nucleus Development
Negative Regulation Of Protein Homotetramerization
Nitric Oxide Homeostasis
Neuromuscular Process
Oxidation-reduction Process
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Cerebellum Maturation
Musculoskeletal Movement, Spinal Reflex Action
Protein Import Into Peroxisome Matrix, Translocation
Regulation Of Inward Rectifier Potassium Channel Activity
Positive Regulation Of Cholesterol Homeostasis
Protein Import Into Peroxisome Matrix, Docking
Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
Gamma-aminobutyric Acid Secretion
Negative Regulation Of Pinocytosis
Caveolin-mediated Endocytosis
Protein Localization To Basolateral Plasma Membrane
Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Acetylcholine Secretion, Neurotransmission
Mammary Gland Involution
Organelle Organization
Cytosolic Calcium Ion Homeostasis
Tagcloud
?
cannabinoid
cannabinoids
cb
chemotactic
chemotaxis
clone
confocal
crosstalk
cxcl12
cxcr4
cytoskeletal
elucidation
healing
innovative
jwh
mcf7
metastasis
mmtv
modulate
nt
orthotopic
p42
p44
possess
psychoactive
pymt
syngenic
tumorigenic
wound
Tagcloud (Difference)
?
cannabinoid
cannabinoids
cb
chemotactic
chemotaxis
clone
confocal
crosstalk
cxcl12
cxcr4
cytoskeletal
elucidation
healing
innovative
jwh
mcf7
metastasis
mmtv
modulate
nt
orthotopic
p42
p44
possess
psychoactive
pymt
syngenic
tumorigenic
wound
Tagcloud (Intersection)
?