PITPNA

Gene Name		phosphatidylinositol transfer protein, alpha
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Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transporter Activity
	Biological Process	Lipid Metabolic Process Axon Guidance Visual Perception Phospholipid Transport
Pathways		Axon guidance Role of second messengers in netrin-1 signaling Netrin-1 signaling
Drugs		1,2-Diacyl-Sn-Glycero-3-Phosphoinositol (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS
Protein-protein Interactions		8 interactors: CSNK2B DCC EGFR NEO1 PI4KA PIK3C3 PLCG1 SCP2
Entrez ID		5306
HPRD ID		02548
Ensembl ID		ENSG00000174238
Uniprot IDs		B4E1U1 Q00169
PDB IDs		1UW5
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Phosphorylation Cell Part Morphogenesis Response To External Stimulus Neuron Development Cellular Lipid Metabolic Process Cell Morphogenesis Phosphatidylinositol-mediated Signaling Neuron Differentiation Cell Projection Organization Locomotion Lipid Metabolic Process Regulation Of Phosphorylation Anatomical Structure Morphogenesis Cellular Response To Epidermal Growth Factor Stimulus Lipid Modification Response To Organic Substance Response To Epidermal Growth Factor Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Protein Phosphorylation Positive Regulation Of Intracellular Transport Regulation Of Protein Kinase Activity Generation Of Neurons Phosphate-containing Compound Metabolic Process Regulation Of Kinase Activity Neurogenesis Regulation Of Blood Vessel Endothelial Cell Migration Cell Development Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Protein Modification Process Cellular Response To Organic Substance Positive Regulation Of Phospholipase C Activity Signal Transduction Activation Of MAPKK Activity Phospholipid Metabolic Process Organophosphate Metabolic Process Response To Stimulus Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Signaling
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