PITPNA and NEO1

Number of citations of the paper that reports this interaction (PMID 16244667)
19

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PITPNA	NEO1
Gene Name		phosphatidylinositol transfer protein, alpha	neogenin 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transporter Activity	Receptor Activity Cadherin Binding
	Biological Process	Lipid Metabolic Process Axon Guidance Visual Perception Phospholipid Transport	Regulation Of Transcription, DNA-templated Cell Adhesion Axon Guidance Myoblast Fusion Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Iron Ion Homeostasis
Pathways		Axon guidance Role of second messengers in netrin-1 signaling Netrin-1 signaling	CDO in myogenesis Axon guidance Myogenesis Netrin-1 signaling
Drugs		1,2-Diacyl-Sn-Glycero-3-Phosphoinositol (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CSNK2B DCC EGFR NEO1 PI4KA PIK3C3 PLCG1 SCP2	4 interactors: NTN1 NTN3 PITPNA PTK2
Entrez ID		5306	4756
HPRD ID		02548	03549
Ensembl ID		ENSG00000174238	ENSG00000067141
Uniprot IDs		B4E1U1 Q00169	Q59FP8 Q92859
PDB IDs		1UW5	1X5F 1X5G 1X5H 1X5I 1X5J 1X5K 3P4L
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Phosphorylation Cell Part Morphogenesis Response To External Stimulus Neuron Development Cellular Lipid Metabolic Process Cell Morphogenesis Phosphatidylinositol-mediated Signaling Neuron Differentiation Cell Projection Organization Locomotion Lipid Metabolic Process Regulation Of Phosphorylation Anatomical Structure Morphogenesis Cellular Response To Epidermal Growth Factor Stimulus Lipid Modification Response To Organic Substance Response To Epidermal Growth Factor Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Protein Phosphorylation Positive Regulation Of Intracellular Transport Regulation Of Protein Kinase Activity Generation Of Neurons Phosphate-containing Compound Metabolic Process Regulation Of Kinase Activity Neurogenesis Regulation Of Blood Vessel Endothelial Cell Migration Cell Development Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Protein Modification Process Cellular Response To Organic Substance Positive Regulation Of Phospholipase C Activity Signal Transduction Activation Of MAPKK Activity Phospholipid Metabolic Process Organophosphate Metabolic Process Response To Stimulus Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Signaling	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Establishment Of Nucleus Localization Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Nucleus Localization Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Negative Regulation Of Axonogenesis Cell Development Response To External Stimulus Negative Regulation Of Developmental Growth Negative Regulation Of Cell Morphogenesis Involved In Differentiation Nervous System Development Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Projection Organization Regulation Of Axonogenesis Neuron Migration Negative Regulation Of Neuron Differentiation Cell Differentiation Negative Regulation Of Growth Netrin-activated Signaling Pathway Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Anterior/posterior Axon Guidance Negative Regulation Of Synapse Assembly System Development Establishment Of Organelle Localization Negative Regulation Of Cell Development Regulation Of Cell Differentiation Signal Complex Assembly Regulation Of Neuron Projection Development Multicellular Organismal Development Organelle Localization Anatomical Structure Development Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization
Tagcloud ?			a9 cd137l colonization ctss dataset deregulated discriminate efna3 elisas forward gdf15 isotope km12c km12sm metastatic midkine orbitrap podxl s100a8 secretome serpini1 silac silico sostdc1 spectrometer tnfsf9 tumorigenic velos zg16b
Tagcloud (Difference) ?			a9 cd137l colonization ctss dataset deregulated discriminate efna3 elisas forward gdf15 isotope km12c km12sm metastatic midkine orbitrap podxl s100a8 secretome serpini1 silac silico sostdc1 spectrometer tnfsf9 tumorigenic velos zg16b
Tagcloud (Intersection) ?