PITPNA and NEO1

Number of citations of the paper that reports this interaction (PubMedID 16244667)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PITPNA	NEO1
Description		phosphatidylinositol transfer protein alpha	neogenin 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleoplasm Golgi Apparatus Plasma Membrane Cell Surface Membrane Growth Cone Intracellular Vesicle Plasma Membrane Protein Complex Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Phospholipid Transporter Activity Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylcholine Binding Phosphatidylinositol Binding Quaternary Ammonium Group Binding Phosphatidylcholine Transfer Activity Phosphatidylglycerol Binding	Protein Binding Signaling Receptor Activity Co-receptor Binding Cadherin Binding BMP Receptor Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Axonogenesis Visual Perception Phospholipid Transport Intermembrane Lipid Transfer	Neuron Migration Regulation Of DNA-templated Transcription Intracellular Iron Ion Homeostasis Cell Adhesion Axon Guidance Myoblast Fusion Protein Secretion Positive Regulation Of BMP Signaling Pathway Regulation Of Axon Regeneration Negative Regulation Of Axon Regeneration Negative Regulation Of Protein Secretion Multicellular Organismal-level Iron Ion Homeostasis Cell-cell Adhesion Trans-synaptic Signaling, Modulating Synaptic Transmission
Pathways		Role of second messengers in netrin-1 signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Netrin-1 signaling Myogenesis
Drugs		1,2-diacyl-sn-glycero-3-phosphoinositol (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS		Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)	Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Dentures ( 31235808) Face memory ( 31596458) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Red cell distribution width ( 32888494) Resting heart rate ( 27798624) Urate levels ( 31578528)
Interacting Genes		9 interacting genes: CSNK2B DCC EGFR NEO1 PI4KA PIK3C3 PLCG1 SCP2 UBC	6 interacting genes: MTDH NTN1 NTN3 PITPNA PTK2 TTN
Entrez ID		5306	4756
HPRD ID		02548	03549
Ensembl ID		ENSG00000174238	ENSG00000067141
Uniprot IDs		B4E1U1 Q00169 V9HWC5	Q59FP8 Q92859
PDB IDs		1UW5 8PQO	1X5F 1X5G 1X5H 1X5I 1X5J 1X5K 3P4L
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol-mediated Signaling Intracellular Vesicle Phosphatidylinositol Metabolic Process Phosphate-containing Compound Metabolic Process Plasma Membrane Cytosol Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Multivesicular Body, Internal Vesicle Lumen Epidermal Growth Factor Receptor Signaling Pathway Phosphatidylinositol Phosphate Biosynthetic Process Glycerophospholipid Metabolic Process Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication Propionyl-CoA C2-trimethyltridecanoyltransferase Activity Propanoyl-CoA C-acyltransferase Activity Cadherin Binding Glycerolipid Metabolic Process Phospholipid Metabolic Process Regulation Of Viral Life Cycle Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Catabolic Process Negative Regulation Of Protein Catabolic Process Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Blood Vessel Endothelial Cell Migration Postsynaptic Density Membrane Dorsal/ventral Axon Guidance Cell Migration Cell Motility Spinal Cord Ventral Commissure Morphogenesis Negative Regulation Of Neuron Projection Development Response To Amino Acid Ruffle Membrane Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Focal Adhesion ERBB Signaling Pathway Epidermal Growth Factor Binding Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Shc-EGFR Complex Lipid Metabolic Process Organophosphate Metabolic Process Peroxisome Host-mediated Perturbation Of Viral Process Positive Regulation Of Protein Lipidation Phosphatidylinositol Biosynthetic Process Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III, Type I Modulation Of Process Of Another Organism Host-mediated Perturbation Of Symbiont Process	Detection Of Muscle Stretch Axon Guidance Axonogenesis Neuron Projection Guidance Anatomical Structure Morphogenesis Response To Muscle Stretch Neuron Projection Morphogenesis Cell Projection Morphogenesis Detection Of Mechanical Stimulus Cell Projection Organization Neuron Projection Development Detection Of Abiotic Stimulus Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Protein Tyrosine Kinase Activity Quaternary Ammonium Group Binding Skeletal Muscle Myosin Thick Filament Assembly Cdc42 Protein Signal Transduction Phosphatidylglycerol Binding Myosin Filament Assembly Plasma Membrane Bounded Cell Projection Organization Phosphatidylcholine Transporter Activity Phosphatidylcholine Transfer Activity Response To Mechanical Stimulus Regulation Of Anatomical Structure Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Positive Regulation Of Macrophage Proliferation Telethonin Binding Skeletal Muscle Thin Filament Assembly Chemorepulsion Of Axon Anterior/posterior Axon Guidance Intercellular Canaliculus Signal Complex Assembly Mammary Gland Duct Morphogenesis Netrin-activated Signaling Pathway Detection Of Stimulus Striated Muscle Thin Filament Regulation Of Cell Junction Assembly Substrate-dependent Cell Migration, Cell Extension Phosphatidylinositol Transfer Activity JUN Kinase Binding Actin Cytoskeleton Protein Kinase A Signaling Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Motor Neuron Migration Cytoplasm Vascular Endothelial Cell Response To Fluid Shear Stress Muscle Alpha-actinin Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?