ATP2A2

Gene Name		ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Intercalated Disc Longitudinal Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Platelet Dense Tubular Network Membrane Sarcoplasmic Reticulum Membrane Calcium Ion-transporting ATPase Complex
	Molecular Function	Calcium-transporting ATPase Activity Calcium Ion Binding Protein Binding ATP Binding Protein C-terminus Binding Enzyme Binding S100 Protein Binding Metal Ion Binding Calcium-transporting ATPase Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Calcium Ion Homeostasis ER-nucleus Signaling Pathway Cell Adhesion Blood Coagulation Metabolic Process Epidermis Development Positive Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Ion Transmembrane Transport Negative Regulation Of Heart Contraction Transmembrane Transport Relaxation Of Cardiac Muscle Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways		Ion transport by P-type ATPases Ion channel transport Pre-NOTCH Processing in Golgi Platelet homeostasis Reduction of cytosolic Ca++ levels Signaling by NOTCH Pre-NOTCH Expression and Processing Platelet calcium homeostasis
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-protein Interactions		9 interactors: BCL2 CAMK2A HGS IRS1 IRS2 MDM2 PLN S100A1 SPP1
Entrez ID		488
HPRD ID		00161
Ensembl ID		ENSG00000174437
Uniprot IDs		P16615
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transport Regulation Of Cellular Localization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Hormone Regulation Of Calcium Ion Transport Regulation Of Ion Transport Defense Response Response To Organic Substance Innate Immune Response Negative Regulation Of Ion Transport Response To Organonitrogen Compound Positive Regulation Of Fatty Acid Beta-oxidation Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Transport Positive Regulation Of Glycogen Biosynthetic Process Cellular Response To Stimulus Response To Peptide Hormone Phosphatidylinositol-mediated Signaling Intracellular Signal Transduction Immune Response-regulating Signaling Pathway Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Fatty Acid Oxidation Response To Steroid Hormone Regulation Of Transmembrane Transporter Activity Response To Peptide Cell Surface Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Immune System Process Cellular Response To Fibroblast Growth Factor Stimulus Signal Transduction Response To Fibroblast Growth Factor Positive Regulation Of Lipid Catabolic Process Cellular Response To Growth Hormone Stimulus Immune Response Neurotrophin TRK Receptor Signaling Pathway Regulation Of Secretion Positive Regulation Of Fatty Acid Metabolic Process Response To Ischemia Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Neurotrophin Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Fc-epsilon Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Response To Stimulus Signaling
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