RPS25 and THAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RPS25	THAP1
Description		ribosomal protein S25	THAP domain containing 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Postsynaptic Density Small Ribosomal Subunit Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Synapse Extracellular Exosome Ribonucleoprotein Complex	Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Cytoplasmic Translation RRNA Processing Translation Ribosomal Small Subunit Biogenesis	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS			Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		15 interacting genes: APP DUX4 HAP1 HMBOX1 HOMEZ NKAPD1 PTEN SGSM2 SLC26A4-AS1 SNCA STAC3 THAP1 TSPYL2 UPF2 ZBTB14	105 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BEND7 BMS1P1 BYSL C1orf216 C1orf35 CDC37 CDKN2D CHD2 CHLSN CSNK2A1 DCAF8 DRC4 DVL2 FAM124A FAM133A FAM9A FGF10 FGF11 FGF12 FXR2 GPATCH2L HNRNPLL HYPK INO80B KANK2 KLF12 KRTAP10-7 L3MBTL2 LASP1 LMNB2 LMO3 LNX1 METTL13 MFAP1 MIS18A MORF4L1 MORF4L2 MRPL11 MRPL53 NDUFAB1 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PHF19 PID1 PNKP POLR2L POLR2M POU6F2 PPIG PRKAA1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RAD54L2 RALY RALYL RBM10 RBM39 RIPPLY1 RNF4 RP9P RPL22 RPS25 SAP30BP SERF2 SLU7 SPANXN2 SPMIP2 SREK1IP1 STRBP TCEA2 TCEANC TPM3 TRAF5 TRIM26 TRIP10 TTLL10 TXN2 U2AF2 UBE2I VCX2 WT1 YES1 ZBTB48 ZCCHC10 ZGPAT ZNF385C ZNF408 ZNF526
Entrez ID		6230	55145
HPRD ID		01593	15496
Ensembl ID		ENSG00000118181	ENSG00000131931
Uniprot IDs		P62851	Q9NVV9
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7QP6 7QP7 7R4X 7TQL 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O	2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		Trans-synaptic Signaling Chemical Synaptic Transmission Synaptic Signaling Cell-cell Signaling Cell Communication Negative Regulation Of Metabolic Process Regulation Of Calcium Ion Transmembrane Transport Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Adult Behavior Growth Cone Regulation Of Presynapse Assembly Regulation Of Monoatomic Ion Transmembrane Transport Amyloid Fibril Formation Positive Regulation Of Synaptic Transmission Negative Regulation Of Macromolecule Metabolic Process Regulation Of Neurotransmitter Uptake Microglial Cell Activation Dendritic Spine Cellular Response To Copper Ion Signaling Regulation Of Monoatomic Cation Transmembrane Transport PML Body Inclusion Body Positive Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Cation Channel Activity Telomeric DNA Binding Response To Copper Ion Regulation Of Monoatomic Ion Transport Positive Regulation Of Excitatory Postsynaptic Potential Reproductive Behavior Leukocyte Activation Involved In Inflammatory Response Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Ion Transmembrane Transporter Activity Identical Protein Binding Positive Regulation Of Transporter Activity Positive Regulation Of Monoatomic Ion Transport Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Modulation Of Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Toll Signaling Pathway Locomotory Behavior Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Synaptic Vesicle Clustering Delta7-sterol 5(6)-desaturase Activity	Nucleus RNA Splicing Nucleic Acid Binding RNA Binding Protein Binding MRNA Processing Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process PTB Domain Binding ESC/E(Z) Complex Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Metabolic Process Positive Regulation Of Fat Cell Proliferation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?