RPS7 and TNPO1

Number of citations of the paper that reports this interaction (PMID 9687515)
135

Data Source:
HPRD (in vitro)

		RPS7	TNPO1
Gene Name		ribosomal protein S7	transportin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex 90S Preribosome Small-subunit Processome Extracellular Vesicular Exosome	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Small Subunit Biogenesis Cellular Protein Metabolic Process	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CDKN2A IPO5 IPO7 MDM2 NEK6 RPS4X TNPO1 UPF2 ZBTB14	17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19
Entrez ID		6201	3842
HPRD ID		04712	04210
Ensembl ID		ENSG00000171863	ENSG00000083312
Uniprot IDs		P62081	Q92973
PDB IDs		3J3A	1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ
Enriched GO Terms of Interacting Partners?		Protein Localization To Nucleus Protein Localization To Organelle Viral Process Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Establishment Of Protein Localization To Organelle Protein Import Into Nucleus Nuclear Import Protein Targeting Protein Import Protein Destabilization Regulation Of Cellular Senescence Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Export From Nucleus Cellular Protein Localization Regulation Of Mitotic Cell Cycle Phase Transition Cellular Localization Regulation Of Cell Cycle Phase Transition Establishment Of Protein Localization Regulation Of Intracellular Protein Transport Intracellular Transport Regulation Of Signal Transduction By P53 Class Mediator Intracellular Protein Transport Protein Localization Positive Regulation Of Cell Cycle Arrest Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Localization In Cell Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Transport Posttranscriptional Regulation Of Gene Expression Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Cell Cycle Arrest Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Cell Cycle Process Regulation Of Response To DNA Damage Stimulus Senescence-associated Heterochromatin Focus Assembly Protein Transport Regulation Of Protein Stability Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Transport Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport Traversing Start Control Point Of Mitotic Cell Cycle Positive Regulation Of Cellular Senescence DNA Damage Checkpoint MRNA Catabolic Process Regulation Of Proteolysis	Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process
Tagcloud ?		3gamma assisted bmecs bovine coimmunoprecipitation coip colocalization desorption eif1ax fingerprinting flight fret interacted ionization isoform maldi mammary methionine mtor positively promote proved resonance stat5 synthesis tof translation trigger triggered	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Difference) ?		3gamma assisted bmecs bovine coimmunoprecipitation coip colocalization desorption eif1ax fingerprinting flight fret interacted ionization isoform maldi mammary methionine mtor positively promote proved resonance stat5 synthesis tof translation trigger triggered	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Intersection) ?