RPS7 and RPS4X

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (pull down, biochemical, biochemical)

		RPS7	RPS4X
Gene Name		ribosomal protein S7	ribosomal protein S4, X-linked
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex 90S Preribosome Small-subunit Processome Extracellular Vesicular Exosome	Cytosol Ribosome Polysome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	Structural Constituent Of Ribosome RRNA Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Small Subunit Biogenesis Cellular Protein Metabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organismal Development Positive Regulation Of Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Positive Regulation Of Translation
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CDKN2A IPO5 IPO7 MDM2 NEK6 RPS4X TNPO1 UPF2 ZBTB14	11 interactors: ARPC3 CAMK2D CTBP2 HNRNPH3 MCM2 RPS15 RPS5 RPS6 RPS7 RPS8 RPS9
Entrez ID		6201	6191
HPRD ID		04712	02427
Ensembl ID		ENSG00000171863
Uniprot IDs		P62081	B2R491 P62701
PDB IDs		3J3A	3J3A
Enriched GO Terms of Interacting Partners?		Protein Localization To Nucleus Protein Localization To Organelle Viral Process Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Establishment Of Protein Localization To Organelle Protein Import Into Nucleus Nuclear Import Protein Targeting Protein Import Protein Destabilization Regulation Of Cellular Senescence Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Export From Nucleus Cellular Protein Localization Regulation Of Mitotic Cell Cycle Phase Transition Cellular Localization Regulation Of Cell Cycle Phase Transition Establishment Of Protein Localization Regulation Of Intracellular Protein Transport Intracellular Transport Regulation Of Signal Transduction By P53 Class Mediator Intracellular Protein Transport Protein Localization Positive Regulation Of Cell Cycle Arrest Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Localization In Cell Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Transport Posttranscriptional Regulation Of Gene Expression Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Cell Cycle Arrest Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Cell Cycle Process Regulation Of Response To DNA Damage Stimulus Senescence-associated Heterochromatin Focus Assembly Protein Transport Regulation Of Protein Stability Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Transport Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport Traversing Start Control Point Of Mitotic Cell Cycle Positive Regulation Of Cellular Senescence DNA Damage Checkpoint MRNA Catabolic Process Regulation Of Proteolysis	Viral Life Cycle Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Translational Termination Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Protein Targeting To Membrane Translational Elongation RNA Catabolic Process Cellular Protein Complex Disassembly Protein Complex Disassembly Establishment Of Protein Localization To Membrane Translational Initiation MRNA Metabolic Process Viral Process Ribosomal Small Subunit Biogenesis Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Aromatic Compound Catabolic Process Protein Localization To Organelle Translation Cytoplasmic Transport RRNA Processing RRNA Metabolic Process Cellular Macromolecule Catabolic Process Membrane Organization Ribosome Biogenesis Intracellular Protein Transport Ribonucleoprotein Complex Biogenesis Ribosomal Small Subunit Assembly Cellular Protein Localization RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Protein Transport Establishment Of Protein Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression RNA Biosynthetic Process Intracellular Transport Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Translational Fidelity Macromolecule Biosynthetic Process
Tagcloud ?		3gamma assisted bmecs bovine coimmunoprecipitation coip colocalization desorption eif1ax fingerprinting flight fret interacted ionization isoform maldi mammary methionine mtor positively promote proved resonance stat5 synthesis tof translation trigger triggered	aberrant blastocyst bovine cattle clones cows embryo embryos freemartin gestation hatched hprt inner lost mecp2 pregnancies recipient reconstructed rq scnt slc25a6 somatic telomerase transcript transfer twin xiap xist zfx
Tagcloud (Difference) ?		3gamma assisted bmecs coimmunoprecipitation coip colocalization desorption eif1ax fingerprinting flight fret interacted ionization isoform maldi mammary methionine mtor positively promote proved resonance stat5 synthesis tof translation trigger triggered	aberrant blastocyst cattle clones cows embryo embryos freemartin gestation hatched hprt inner lost mecp2 pregnancies recipient reconstructed rq scnt slc25a6 somatic telomerase transcript transfer twin xiap xist zfx
Tagcloud (Intersection) ?		bovine