CCDC90B and AGR2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC90B	AGR2
Gene Name		coiled-coil domain containing 90B	anterior gradient 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane	Extracellular Region Mitochondrion Endoplasmic Reticulum
	Molecular Function		Dystroglycan Binding Protein Binding
	Biological Process		Lung Goblet Cell Differentiation Mucus Secretion
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Protein-Protein Interactions		29 interactors: AGR2 ANXA7 ARL15 BTBD2 CDKN2B CDKN2C DLEU1 DNM2 EIF2S2 FXYD6 KDM1A LAMTOR1 NACA NIPSNAP3A PAFAH1B3 PCDHA4 PIN1 PNP PRDX5 PSMD11 RGL2 RNF10 SAT1 SDHAF2 SERPINB9 SMN1 TAC3 TK1 TSC22D1	15 interactors: APP BRD7 CATSPER1 CCDC90B CRMP1 DAG1 FABP2 KRT31 LYPD3 MED31 MLH1 NUP62CL POM121 UBQLN1 UBQLN4
Entrez ID		60492	10551
HPRD ID		14378	05896
Ensembl ID		ENSG00000137500	ENSG00000106541
Uniprot IDs		B3KP87 Q9GZT6	O95994 Q4JM46
PDB IDs			2LNS 2LNT
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Proliferation Developmental Process System Development Anatomical Structure Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cellular Protein Metabolic Process Nucleoside Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleotide Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Multicellular Organismal Development Reactive Nitrogen Species Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Catalytic Activity Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Cell Differentiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Inosine Catabolic Process Regulation Of Apoptosis Involved In Tissue Homeostasis Regulation Of Primitive Erythrocyte Differentiation Nicotinamide Riboside Catabolic Process Fetal Process Involved In Parturition Mitochondrial Electron Transport, Succinate To Ubiquinone NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Membrane Tubulation Mucus Secretion Spermidine Acetylation Skeletal Muscle Cell Proliferation Interleukin-2 Secretion Urate Biosynthetic Process Purine Nucleoside Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Cellular Nitrogen Compound Metabolic Process Regulation Of Oxidoreductase Activity Endosome Localization Lung Goblet Cell Differentiation Protein-FAD Linkage Regulation Of Cholesterol Import Putrescine Catabolic Process Positive Regulation Of Skeletal Muscle Tissue Growth Response To Stimulus
Tagcloud ?			aacr acting adenocarcinomas autonomous besides coordinated disulfide drives exerting fibroblast fibroblasts folding gastric hypoxic incorporated isomerase microenvironment neoplastic organs paracrine participates physiologically res residing signet srcc stromal surrounding turn
Tagcloud (Difference) ?			aacr acting adenocarcinomas autonomous besides coordinated disulfide drives exerting fibroblast fibroblasts folding gastric hypoxic incorporated isomerase microenvironment neoplastic organs paracrine participates physiologically res residing signet srcc stromal surrounding turn
Tagcloud (Intersection) ?