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CCDC90B and CDKN2C
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCDC90B
CDKN2C
Gene Name
coiled-coil domain containing 90B
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Integral Component Of Membrane
Nucleus
Cytoplasm
Cytosol
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Protein Kinase Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Cell Cycle Arrest
Negative Regulation Of Cell Proliferation
Negative Regulation Of Cell Growth
Negative Regulation Of Phosphorylation
Oligodendrocyte Differentiation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Cyclin D associated events in G1
Oxidative Stress Induced Senescence
G1 Phase
Cellular Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
Mitotic G1-G1/S phases
Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Ventricular conduction (
21076409
)
Protein-Protein Interactions
29 interactors:
AGR2
ANXA7
ARL15
BTBD2
CDKN2B
CDKN2C
DLEU1
DNM2
EIF2S2
FXYD6
KDM1A
LAMTOR1
NACA
NIPSNAP3A
PAFAH1B3
PCDHA4
PIN1
PNP
PRDX5
PSMD11
RGL2
RNF10
SAT1
SDHAF2
SERPINB9
SMN1
TAC3
TK1
TSC22D1
27 interactors:
AHCYL1
APLP1
ATM
ATR
CCDC90B
CDK4
CDK6
CDKN2A
COPS6
DRAP1
GDF9
GOPC
LRIF1
LY96
MAPK10
MAPK8
NAGK
NHP2L1
NIF3L1
PPP2CA
RBM48
REL
TCF12
TCF4
TLE1
TP53
UNC119
Entrez ID
60492
1031
HPRD ID
14378
04534
Ensembl ID
ENSG00000137500
ENSG00000123080
Uniprot IDs
B3KP87
Q9GZT6
P42773
Q6ICV4
PDB IDs
1BU9
1G3N
1IHB
1MX2
1MX4
1MX6
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Proliferation
Developmental Process
System Development
Anatomical Structure Development
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cellular Protein Metabolic Process
Nucleoside Metabolic Process
Negative Regulation Of Protein Metabolic Process
Nucleotide Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Multicellular Organismal Development
Reactive Nitrogen Species Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Apoptotic Process
Regulation Of Cell Death
Regulation Of Cell Differentiation
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development
Inosine Catabolic Process
Regulation Of Apoptosis Involved In Tissue Homeostasis
Regulation Of Primitive Erythrocyte Differentiation
Nicotinamide Riboside Catabolic Process
Fetal Process Involved In Parturition
Mitochondrial Electron Transport, Succinate To Ubiquinone
NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway
Negative Regulation Of Catalytic Activity
Positive Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Membrane Tubulation
Mucus Secretion
Spermidine Acetylation
Skeletal Muscle Cell Proliferation
Interleukin-2 Secretion
Urate Biosynthetic Process
Purine Nucleoside Metabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Cellular Nitrogen Compound Metabolic Process
Regulation Of Oxidoreductase Activity
Endosome Localization
Lung Goblet Cell Differentiation
Protein-FAD Linkage
Regulation Of Cholesterol Import
Putrescine Catabolic Process
Positive Regulation Of Skeletal Muscle Tissue Growth
Response To Stimulus
Replicative Senescence
Regulation Of Gene Expression
Regulation Of Protein Metabolic Process
Regulation Of Metabolic Process
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Signal Transduction
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Cell Cycle Arrest
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Process
Cell Aging
Positive Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Cell Cycle Arrest
Mitotic Cell Cycle Process
RNA Metabolic Process
Cell Cycle
Negative Regulation Of Growth
Regulation Of Intracellular Signal Transduction
Response To Radiation
Negative Regulation Of Cell Cycle
Regulation Of Signal Transduction
Signal Transduction
Mitotic Cell Cycle
JUN Phosphorylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cell Death
Positive Regulation Of Cell Aging
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Signaling
Negative Regulation Of Cell Growth
Response To Gamma Radiation
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Response To Light Stimulus
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Apoptotic Process
Cell Communication
Positive Regulation Of Programmed Cell Death
Cellular Metabolic Process
Cellular Response To Ionizing Radiation
Positive Regulation Of Cell Death
Tagcloud
?
a134c
abp
allelic
ankyrin
balb
cdk6
cdnas
chr
congenic
d2
dba
g232a
ifna
inbred
inefficient
ink4c
le
multigenic
mus
p15
p16
p18
pctr1
plasmacytoma
pristane
spretus
typed
Tagcloud (Difference)
?
a134c
abp
allelic
ankyrin
balb
cdk6
cdnas
chr
congenic
d2
dba
g232a
ifna
inbred
inefficient
ink4c
le
multigenic
mus
p15
p16
p18
pctr1
plasmacytoma
pristane
spretus
typed
Tagcloud (Intersection)
?