CCDC90B and LAMTOR1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC90B	LAMTOR1
Gene Name		coiled-coil domain containing 90B	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome Ragulator Complex
	Molecular Function		Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process		Regulation Of Receptor Recycling Endosome Organization Lysosome Organization Regulation Of Cholesterol Esterification Regulation Of Cholesterol Efflux Cell Growth Positive Regulation Of TOR Signaling Lysosome Localization Endosome Localization Cellular Protein Localization Cholesterol Homeostasis Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Regulation Of Cholesterol Import Cellular Response To Amino Acid Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: AGR2 ANXA7 ARL15 BTBD2 CDKN2B CDKN2C DLEU1 DNM2 EIF2S2 FXYD6 KDM1A LAMTOR1 NACA NIPSNAP3A PAFAH1B3 PCDHA4 PIN1 PNP PRDX5 PSMD11 RGL2 RNF10 SAT1 SDHAF2 SERPINB9 SMN1 TAC3 TK1 TSC22D1	4 interactors: ABCF3 CAPN1 CCDC90B EEF1A1
Entrez ID		60492	55004
HPRD ID		14378	07933
Ensembl ID		ENSG00000137500	ENSG00000149357
Uniprot IDs		B3KP87 Q9GZT6	F5H479 Q6IAA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Proliferation Developmental Process System Development Anatomical Structure Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cellular Protein Metabolic Process Nucleoside Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleotide Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Multicellular Organismal Development Reactive Nitrogen Species Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Catalytic Activity Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Cell Differentiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Inosine Catabolic Process Regulation Of Apoptosis Involved In Tissue Homeostasis Regulation Of Primitive Erythrocyte Differentiation Nicotinamide Riboside Catabolic Process Fetal Process Involved In Parturition Mitochondrial Electron Transport, Succinate To Ubiquinone NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Membrane Tubulation Mucus Secretion Spermidine Acetylation Skeletal Muscle Cell Proliferation Interleukin-2 Secretion Urate Biosynthetic Process Purine Nucleoside Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Cellular Nitrogen Compound Metabolic Process Regulation Of Oxidoreductase Activity Endosome Localization Lung Goblet Cell Differentiation Protein-FAD Linkage Regulation Of Cholesterol Import Putrescine Catabolic Process Positive Regulation Of Skeletal Muscle Tissue Growth Response To Stimulus
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