BCL2 and BIK

  • Number of citations of the paper that reports this interaction (PMID 16697956)
  • 236
  • Data Source:
  • HPRD (in vivo, in vitro)

BCL2

BIK

Gene Name B-cell CLL/lymphoma 2 BCL2-interacting killer (apoptosis-inducing)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 83 interactors: ATP2A2 BAD BAG1 BAG3 BAG4 BAK1 BAX BBC3 BCAP31 BCL2L1 BCL2L10 BCL2L11 BCL2L14 BCLAF1 BECN1 BFAR BID BIK BLK BMF BNIP1 BNIP2 BNIP3 BNIP3L BNIPL CAPN2 CASP3 CASP8 CDK1 CDK2 CPT1A CYCS EPHB2 FKBP8 HNRNPD HRAS HRK HSPA1A ITM2B ITPR1 KRAS MAPK1 MAPK11 MAPK14 MAPK3 MAPK8 MEX3D MOAP1 MYC NLRP1 NMT2 NR4A1 NRAS PARP1 PIN1 PKMYT1 PMAIP1 PML PPID PPP1CA PPP2CA PPP2R4 PPP2R5A PPP3CA PPP3CC PRKACA PRKCA PSEN1 PXN RAD9A RAF1 RRAS RTN4 SF1 SMN1 SOD1 SPNS1 SQSTM1 TMBIM6 TOMM20 TP53 TP53AIP1 TP53BP2 11 interactors: APP BCL2 BCL2A1 BCL2L1 BCL2L2 CRKL FATE1 MCL1 NR2F2 SOCS3 TANK
Entrez ID 596 638
HPRD ID 01045 04547
Ensembl ID ENSG00000171791 ENSG00000100290
Uniprot IDs C9JHD5 P10415 Q13323
PDB IDs 1G5M 1GJH 1YSW 2O21 2O22 2O2F 2W3L 2XA0 4AQ3 4IEH 4LVT 4LXD 4LXE 2IPE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenocarcinomas  anthracene  carcinogenic  chorionic  dawley  dimethylbenz  dmba  elevation  exists  glands  gonadotropin  hcg  ice  iu  makes  mammary  modulated  myc  ovaries  phenomenon  probed  programmed  rnas  sprague  trpm2  virgin  xl  xs 
abt  actinomycin  antagonism  antagonizing  bak  bcl  bh3  carfilzomib  concurrent  crc  cyclohexamide  ectopic  ectopically  enabled  irreversible  isogenic  kras  mimetic  noxa  overcome  potently  sensitized  sequestered  shrna  synergistic  synergistically  synergy  ultimately  xl 
Tagcloud (Difference) ?
adenocarcinomas  anthracene  carcinogenic  chorionic  dawley  dimethylbenz  dmba  elevation  exists  glands  gonadotropin  hcg  ice  iu  makes  mammary  modulated  myc  ovaries  phenomenon  probed  programmed  rnas  sprague  trpm2  virgin  xs 
abt  actinomycin  antagonism  antagonizing  bak  bh3  carfilzomib  concurrent  crc  cyclohexamide  ectopic  ectopically  enabled  irreversible  isogenic  kras  mimetic  noxa  overcome  potently  sensitized  sequestered  shrna  synergistic  synergistically  synergy  ultimately 
Tagcloud (Intersection) ?
bcl  xl