BCL2 and BCL2L11

  • Number of citations of the paper that reports this interaction (PMID 16697956)
  • 236
  • Data Source:
  • HPRD (in vivo, in vitro)

BCL2

BCL2L11

Gene Name B-cell CLL/lymphoma 2 BCL2-like 11 (apoptosis facilitator)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic lymphocytic leukemia ( 18758461)
  • Dehydroepiandrosterone sulphate levels ( 21533175)
  • Primary sclerosing cholangitis ( 21151127)
Protein-Protein Interactions 83 interactors: ATP2A2 BAD BAG1 BAG3 BAG4 BAK1 BAX BBC3 BCAP31 BCL2L1 BCL2L10 BCL2L11 BCL2L14 BCLAF1 BECN1 BFAR BID BIK BLK BMF BNIP1 BNIP2 BNIP3 BNIP3L BNIPL CAPN2 CASP3 CASP8 CDK1 CDK2 CPT1A CYCS EPHB2 FKBP8 HNRNPD HRAS HRK HSPA1A ITM2B ITPR1 KRAS MAPK1 MAPK11 MAPK14 MAPK3 MAPK8 MEX3D MOAP1 MYC NLRP1 NMT2 NR4A1 NRAS PARP1 PIN1 PKMYT1 PMAIP1 PML PPID PPP1CA PPP2CA PPP2R4 PPP2R5A PPP3CA PPP3CC PRKACA PRKCA PSEN1 PXN RAD9A RAF1 RRAS RTN4 SF1 SMN1 SOD1 SPNS1 SQSTM1 TMBIM6 TOMM20 TP53 TP53AIP1 TP53BP2 26 interactors: AKT1 APP ATP6V1G1 AURKB BCL2 BCL2A1 BCL2L1 BCL2L2 BTK DYNLL1 DYNLL2 FEM1C FGL1 GNB2L1 GTF2I MAGEA11 MAPK10 MAPK8 MAPK9 MCL1 MEX3D RIOK3 SMARCB1 TRIM2 VDAC1 YWHAB
Entrez ID 596 10018
HPRD ID 01045 04828
Ensembl ID ENSG00000171791 ENSG00000153094
Uniprot IDs C9JHD5 P10415 O43521
PDB IDs 1G5M 1GJH 1YSW 2O21 2O22 2O2F 2W3L 2XA0 4AQ3 4IEH 4LVT 4LXD 4LXE 1F95 2K7W 2NL9 2V6Q 2VM6 2WH6 2YQ6 3D7V 3FDL 3IO8 3IO9 3KJ0 3KJ1 3KJ2 4B4S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenocarcinomas  anthracene  carcinogenic  chorionic  dawley  dimethylbenz  dmba  elevation  exists  glands  gonadotropin  hcg  ice  iu  makes  mammary  modulated  myc  ovaries  phenomenon  probed  programmed  rnas  sprague  trpm2  virgin  xl  xs 
akt1  antipsychotic  atg  atg12  atg4b  atg5  atg7  autophagic  autophagosome  autophagosomes  autophagy  bak1  becn1  cdkn1a  cdkn1b  chloroquine  colocalization  dysfunctional  gabarap  henceforth  lc3b  map1lc3b  olanzapine  overtly  pmaip1  sqstm1  sy5y  trp53  unmask 
Tagcloud (Difference) ?
adenocarcinomas  anthracene  carcinogenic  chorionic  dawley  dimethylbenz  dmba  elevation  exists  glands  gonadotropin  hcg  ice  iu  makes  mammary  modulated  myc  ovaries  phenomenon  probed  programmed  rnas  sprague  trpm2  virgin  xl  xs 
akt1  antipsychotic  atg  atg12  atg4b  atg5  atg7  autophagic  autophagosome  autophagosomes  autophagy  bak1  becn1  cdkn1a  cdkn1b  chloroquine  colocalization  dysfunctional  gabarap  henceforth  lc3b  map1lc3b  olanzapine  overtly  pmaip1  sqstm1  sy5y  trp53  unmask 
Tagcloud (Intersection) ?