RAF1 and MAP3K5

  • Number of citations of the paper that reports this interaction (PMID 11427728)
  • 58
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vivo, in vitro)

RAF1

MAP3K5

Gene Name Raf-1 proto-oncogene, serine/threonine kinase mitogen-activated protein kinase kinase kinase 5
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 123 interactors: ADCY6 AGTR1 AKT1 AR ARRB2 BAD BAG1 BCL2 BCL2L1 BCL6 BIRC2 BIRC3 BRAF CCT3 CDC25A CFLAR CNKSR1 COPS3 COPS7A CPS1 DCAF8 DMPK EFEMP1 ERBB2IP FYCO1 FYN GNB2 GNG4 GRB10 HRAS HSP90AA1 HSPA4 HSPA8 IL2RB INSR INTS10 JAK1 JAK2 KRAS KRT18 KRT8 KSR1 KSR2 LCK LRPAP1 MAP2K1 MAP2K2 MAP3K1 MAP3K5 MAPK1 MAPK3 MAPK7 MAPK8 MAPK8IP3 MRAS MYBPC1 MYC NEDD4 NPLOC4 NR3C1 NRAS NUDT14 OIP5 PACSIN3 PAK1 PAK2 PAK3 PBK PDGFRB PEBP1 PEBP4 PEX5L PHB PHKA2 PIN1 PKM PPP1CC PPP2CB PRKAA1 PRKACA PRKAR1A PRKCA PRKCD PRKCE PRKCZ PRKG1 PRPF6 PURA RANBP9 RAP1A RAP2A RASD2 RB1 RBBP8 RBL2 RFXANK RHEB RRAS RRAS2 RSU1 SHOC2 SPRY2 SPRY4 SRC STK26 STK3 STUB1 TBXA2R TIMM50 TMEM70 TSC22D3 UBC UBE2D2 VAV1 VDAC1 XIAP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ YY1 50 interactors: AKT1 AKT2 ARRB1 ARRB2 CDC25A CDKN1A CREBBP DAB2IP DAXX DMD DUSP19 EIF2AK2 EP300 ERN1 GADD45B GEMIN5 GLRX GSTM1 HSPA1A IGF1R JAK2 MAP2K4 MAP2K6 MAP2K7 MAP3K2 MAP3K3 MAP3K6 MAP3K7 MAPK8IP3 MBP NEDD4 NEDD4L PDCD6 PPP3R1 PPP5C PTPN11 QARS RAF1 SFN TNNT2 TPD52L1 TRAF2 TRAF5 TRAF6 TXN USP9X YWHAE YWHAH YWHAQ YWHAZ
Entrez ID 5894 4217
HPRD ID 01265 03904
Ensembl ID ENSG00000132155 ENSG00000197442
Uniprot IDs B4E0X2 L7RRS6 P04049 Q99683
PDB IDs 1C1Y 1FAQ 1FAR 1GUA 1RFA 3CU8 3IQJ 3IQU 3IQV 3KUC 3KUD 3NKX 3O8I 3OMV 4FJ3 4G0N 4G3X 4IEA 4IHL 2CLQ 3VW6 4BF2 4BHN 4BIB 4BIC 4BID 4BIE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
199a2  angptl2  awry  chondrosarcoma  cmet  discovering  dnm3  evenly  fibrosarcoma  flt1  flt4  foxl1  genetics  gli1  hif1alpha  hmga2  kdr  liposarcoma  mdk  med12  muc4  mycn  osteocytes  pcsk1  relentless  sarcoma  tek  tie1  yeats4 
Tagcloud (Difference) ?
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
199a2  angptl2  awry  chondrosarcoma  cmet  discovering  dnm3  evenly  fibrosarcoma  flt1  flt4  foxl1  genetics  gli1  hif1alpha  hmga2  kdr  liposarcoma  mdk  med12  muc4  mycn  osteocytes  pcsk1  relentless  sarcoma  tek  tie1  yeats4 
Tagcloud (Intersection) ?