RAF1 and SHOC2

  • Number of citations of the paper that reports this interaction (PMID 10783161)
  • 36
  • Data Source:
  • HPRD (in vivo, in vitro)

RAF1

SHOC2

Gene Name Raf-1 proto-oncogene, serine/threonine kinase soc-2 suppressor of clear homolog (C. elegans)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 123 interactors: ADCY6 AGTR1 AKT1 AR ARRB2 BAD BAG1 BCL2 BCL2L1 BCL6 BIRC2 BIRC3 BRAF CCT3 CDC25A CFLAR CNKSR1 COPS3 COPS7A CPS1 DCAF8 DMPK EFEMP1 ERBB2IP FYCO1 FYN GNB2 GNG4 GRB10 HRAS HSP90AA1 HSPA4 HSPA8 IL2RB INSR INTS10 JAK1 JAK2 KRAS KRT18 KRT8 KSR1 KSR2 LCK LRPAP1 MAP2K1 MAP2K2 MAP3K1 MAP3K5 MAPK1 MAPK3 MAPK7 MAPK8 MAPK8IP3 MRAS MYBPC1 MYC NEDD4 NPLOC4 NR3C1 NRAS NUDT14 OIP5 PACSIN3 PAK1 PAK2 PAK3 PBK PDGFRB PEBP1 PEBP4 PEX5L PHB PHKA2 PIN1 PKM PPP1CC PPP2CB PRKAA1 PRKACA PRKAR1A PRKCA PRKCD PRKCE PRKCZ PRKG1 PRPF6 PURA RANBP9 RAP1A RAP2A RASD2 RB1 RBBP8 RBL2 RFXANK RHEB RRAS RRAS2 RSU1 SHOC2 SPRY2 SPRY4 SRC STK26 STK3 STUB1 TBXA2R TIMM50 TMEM70 TSC22D3 UBC UBE2D2 VAV1 VDAC1 XIAP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ YY1 6 interactors: APP ERBB2IP HRAS KRAS NRAS RAF1
Entrez ID 5894 8036
HPRD ID 01265 04144
Ensembl ID ENSG00000132155 ENSG00000108061
Uniprot IDs B4E0X2 L7RRS6 P04049 Q9UQ13
PDB IDs 1C1Y 1FAQ 1FAR 1GUA 1RFA 3CU8 3IQJ 3IQU 3IQV 3KUC 3KUD 3NKX 3O8I 3OMV 4FJ3 4G0N 4G3X 4IEA 4IHL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
aortic  associates  biopsies  cardiac  cardiomyocytes  clear  clearly  constriction  decompensated  died  elucidated  erbb2  erbin  erk  explored  failing  heart  hearts  homolog  hypertrophy  interacting  isoproterenol  modulating  overload  participates  raf  rapidly  soc  widely 
Tagcloud (Difference) ?
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
aortic  associates  biopsies  cardiac  cardiomyocytes  clear  clearly  constriction  decompensated  died  elucidated  erbb2  erbin  erk  explored  failing  heart  hearts  homolog  hypertrophy  interacting  isoproterenol  modulating  overload  participates  raf  rapidly  soc  widely 
Tagcloud (Intersection) ?