RASSF5 and LSM7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RASSF5	LSM7
Gene Name		Ras association (RalGDS/AF-6) domain family member 5	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Spliceosomal Complex Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding U6 SnRNA Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Protein Localization To Nucleus	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		31 interactors: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MAP1S MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK3 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 VPS28	23 interactors: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF TACC1 ZSCAN26
Entrez ID		83593	51690
HPRD ID		06117	06287
Ensembl ID		ENSG00000136653	ENSG00000130332
Uniprot IDs		Q8WWW0	Q9UK45
PDB IDs		4LGD
Enriched GO Terms of Interacting Partners?		Ras Protein Signal Transduction Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Signaling Cell Communication Regulation Of Signaling Response To Stimulus Branching Morphogenesis Of An Epithelial Tube Regulation Of Phosphorylation Rap Protein Signal Transduction Positive Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Epithelial Tube Morphogenesis Morphogenesis Of A Branching Epithelium Regulation Of MAPK Cascade Morphogenesis Of A Branching Structure Regulation Of Phosphorus Metabolic Process Tube Morphogenesis Endocardium Development Regulation Of Cell Death Positive Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Neuron Death Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Morphogenesis Of An Epithelium Positive Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Neuron Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Hippo Signaling Neurotrophin Signaling Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Tissue Morphogenesis Regulation Of Synaptic Transmission, GABAergic See more	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Metabolic Process RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions Nuclear-transcribed MRNA Catabolic Process RNA Processing MRNA Catabolic Process RNA Catabolic Process MRNA Splicing, Via Spliceosome Aromatic Compound Catabolic Process RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Gene Expression Spliceosomal SnRNP Assembly Cellular Macromolecule Catabolic Process Histone MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process NcRNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Catabolic Process RRNA Processing RRNA Metabolic Process Termination Of RNA Polymerase II Transcription Ribosome Biogenesis Histone H3-K4 Acetylation Positive Regulation Of Histone Deubiquitination Notochord Cell Development Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Positive Regulation Of Hemoglobin Biosynthetic Process Cellular Metabolic Process DNA-templated Transcription, Termination Metabolic Process MRNA 3'-end Processing Cellular Macromolecular Complex Assembly Axial Mesoderm Formation Retrograde Transport, Plasma Membrane To Golgi RNA 3'-end Processing Regulation Of Hemoglobin Biosynthetic Process Notochord Formation Regulation Of Protein Deubiquitination Lens Fiber Cell Morphogenesis Axial Mesoderm Morphogenesis Regulation Of Protein Localization See more
Tagcloud ?		action activates acts allows arrest catenin dictate effector exhibit explanation frequently ikappab ligase lost nore1a observation oncogene promoted promoting proteasome scf stimulate substrate suppressor toward trcp ubiquitin wnt	angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Difference) ?		action activates acts allows arrest catenin dictate effector exhibit explanation frequently ikappab ligase lost nore1a observation oncogene promoted promoting proteasome scf stimulate substrate suppressor toward trcp ubiquitin wnt	angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Intersection) ?