RASSF5 and RALA

Number of citations of the paper that reports this interaction (PubMedID 9488663)
0

Data Source:
HPRD (two hybrid)

		RASSF5	RALA
Description		Ras association domain family member 5	RAS like proto-oncogene A
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Microtubule	Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Membrane Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body Synaptic Membrane Schaffer Collateral - CA1 Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Apoptotic Process Signal Transduction Positive Regulation Of Protein Ubiquitination Lymphocyte Proliferation Negative Regulation Of Lymphocyte Proliferation Regulation Of Protein Localization To Nucleus	Neural Tube Closure Exocytosis Chemotaxis Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Receptor Internalization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)
Interacting Genes		30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 UBQLN2 VPS28	31 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 SNCA YBX3
Entrez ID		83593	5898
HPRD ID		06117	01549
Ensembl ID		ENSG00000266094	ENSG00000006451
Uniprot IDs		A8K5F3 Q8WWW0	P11233
PDB IDs		4LGD 4OH8	1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O 7NQC 8FJH 8FJI
Enriched GO Terms of Interacting Partners?		GDP Binding Intracellular Signaling Cassette Small GTPase-mediated Signal Transduction Intracellular Signal Transduction G Protein Activity Ras Protein Signal Transduction GTPase Activity GTP Binding Signal Transduction Cytosol Rap Protein Signal Transduction Regulation Of Intracellular Signal Transduction Protein-containing Complex Binding Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Schwann Cell Migration Regulation Of Signal Transduction Regulation Of Protein Modification Process Regulation Of MAPK Cascade Non-canonical NF-kappaB Signal Transduction Regulation Of Protein Catabolic Process Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Branching Morphogenesis Of An Epithelial Tube Nucleotide Binding Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of JNK Cascade Thioesterase Binding Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Canonical NF-kappaB Signal Transduction Cytoplasmic Vesicle Membrane Morphogenesis Of An Epithelium Hydrolase Activity Macromolecule Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Modification-dependent Protein Catabolic Process Regulation Of Protein Stability Positive Regulation Of Protein Modification Process Positive Regulation Of ERAD Pathway Positive Regulation Of Protein Catabolic Process Bounding Membrane Of Organelle Regulation Of Protein Phosphorylation Regulation Of Glial Cell Migration Autophagosome Assembly	Vesicle Tethering Involved In Exocytosis Exocyst Vesicle Tethering Vesicle Docking Involved In Exocytosis Membrane Fission Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Mitotic Cytokinesis Exocytosis Cytoskeleton-dependent Cytokinesis Golgi To Plasma Membrane Transport Vesicle-mediated Transport To The Plasma Membrane Secretion By Cell Organelle Localization Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Small GTPase Binding Secretion Membrane Organization Intracellular Protein Localization Flemming Body Establishment Of Protein Localization Localization Within Membrane Protein Transport Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of Norepinephrine Uptake Regulation Of Ral Protein Signal Transduction Transporter Regulator Activity Ras Protein Signal Transduction Cellular Localization Intracellular Signaling Cassette Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Cytoplasm Plasma Membrane Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Macrophage Differentiation Growth Cone Membrane Regulation Of Autophagy Platelet Aggregation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Growth Cone Small GTPase-mediated Signal Transduction Positive Regulation Of Hormone Secretion Homotypic Cell-cell Adhesion Cytosol Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion
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