RASSF5 and RASSF2

Number of citations of the paper that reports this interaction (PMID 11857081)
43

Data Source:
BioGRID (two hybrid, pull down)

		RASSF5	RASSF2
Gene Name		Ras association (RalGDS/AF-6) domain family member 5	Ras association (RalGDS/AF-6) domain family member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Nucleus Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Protein Localization To Nucleus	Skeletal System Development Ossification Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway Via I-kappaB Kinase/NF-kappaB Cascade Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Bone Remodeling Homeostasis Of Number Of Cells Negative Regulation Of NIK/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		31 interactors: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MAP1S MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK3 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 VPS28	8 interactors: HRAS KDM1A KRAS PRMT3 PRMT6 RASSF5 STK3 SUV39H1
Entrez ID		83593	9770
HPRD ID		06117	15218
Ensembl ID		ENSG00000136653	ENSG00000101265
Uniprot IDs		Q8WWW0	P50749
PDB IDs		4LGD
Enriched GO Terms of Interacting Partners?		Ras Protein Signal Transduction Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Signaling Cell Communication Regulation Of Signaling Response To Stimulus Branching Morphogenesis Of An Epithelial Tube Regulation Of Phosphorylation Rap Protein Signal Transduction Positive Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Epithelial Tube Morphogenesis Morphogenesis Of A Branching Epithelium Regulation Of MAPK Cascade Morphogenesis Of A Branching Structure Regulation Of Phosphorus Metabolic Process Tube Morphogenesis Endocardium Development Regulation Of Cell Death Positive Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Neuron Death Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Morphogenesis Of An Epithelium Positive Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Neuron Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Hippo Signaling Neurotrophin Signaling Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Tissue Morphogenesis Regulation Of Synaptic Transmission, GABAergic	Positive Regulation Of Rac Protein Signal Transduction Histone Modification Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Methylation Regulation Of Cellular Protein Metabolic Process Peptidyl-arginine N-methylation Regulation Of Protein Metabolic Process Histone Arginine Methylation Protein Methylation Peptidyl-arginine Methylation Chromatin Modification Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Cell Proliferation Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Organization Regulation Of RNA Metabolic Process Regulation Of Synaptic Transmission, GABAergic Regulation Of Rac Protein Signal Transduction Social Behavior Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of Metabolic Process Regulation Of Gene Expression Epithelial Tube Branching Involved In Lung Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Positive Regulation Of Protein Modification Process Muscle Cell Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Ras Protein Signal Transduction Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Small GTPase Mediated Signal Transduction Visual Learning Response To Stress Chromosome Organization Visual Behavior Activation Of MAPKK Activity Lung Morphogenesis Epithelial Tube Morphogenesis Methylation Blood Coagulation Positive Regulation Of Cellular Protein Metabolic Process Hemostasis Tube Morphogenesis Positive Regulation Of MAPK Cascade Associative Learning Regulation Of Primitive Erythrocyte Differentiation
Tagcloud ?		action activates acts allows arrest catenin dictate effector exhibit explanation frequently ikappab ligase lost nore1a observation oncogene promoted promoting proteasome scf stimulate substrate suppressor toward trcp ubiquitin wnt	23h1 aberrations birc5 ccne2 ctsb dab2 ddx15 dismal egr1 etv4 eya4 gata3 gltscr2 hmmr itgb4 kcnk12 lama3 licam2 loxl2 metastasize mmp13 mpnst mpnsts msh2 pdgfra rhamm sult2a1 tff top2a
Tagcloud (Difference) ?		action activates acts allows arrest catenin dictate effector exhibit explanation frequently ikappab ligase lost nore1a observation oncogene promoted promoting proteasome scf stimulate substrate suppressor toward trcp ubiquitin wnt	23h1 aberrations birc5 ccne2 ctsb dab2 ddx15 dismal egr1 etv4 eya4 gata3 gltscr2 hmmr itgb4 kcnk12 lama3 licam2 loxl2 metastasize mmp13 mpnst mpnsts msh2 pdgfra rhamm sult2a1 tff top2a
Tagcloud (Intersection) ?