RAB27A and RBM48

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAB27A	RBM48
Description		RAB27A, member RAS oncogene family	RNA binding motif protein 48
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Extracellular Region Lysosome Endosome Late Endosome Golgi Apparatus Cytosol Membrane Apical Plasma Membrane Secretory Granule Dendrite Multivesicular Body Membrane Weibel-Palade Body Melanosome Membrane Specific Granule Lumen Melanosome Extracellular Exosome Exocytic Vesicle	Nucleoplasm Spliceosomal Complex
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein Domain Specific Binding Myosin V Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Exocytosis Blood Coagulation Protein Secretion Positive Regulation Of Gene Expression Vesicle-mediated Transport Antigen Processing And Presentation Melanocyte Differentiation Melanosome Localization Melanosome Transport Multivesicular Body Organization Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Pigmentation Positive Regulation Of Exocytosis Synaptic Vesicle Transport Positive Regulation Of Phagocytosis Pigment Granule Localization Pigment Granule Transport Multivesicular Body Sorting Pathway Complement-dependent Cytotoxicity Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Constitutive Secretory Pathway Exosomal Secretion	MRNA Processing RNA Splicing
Pathways		Insulin processing Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Regulation of MITF-M-dependent genes involved in pigmentation
Drugs
Diseases		Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Fractional exhaled nitric oxide levels ( 25431337) Glioma ( 30714141)	Hip circumference adjusted for BMI ( 34021172) Idiopathic dilated cardiomyopathy ( 29495422)
Interacting Genes		28 interacting genes: ADRB2 APP CEP126 COPS6 EEF1A1 ERG28 EXPH5 GDF9 GDI1 GZMB LRIF1 MLPH MYO5A MYRIP RABGGTB RBM48 RIMS1 RIMS2 RPH3A RPH3AL STX1A SYTL1 SYTL2 SYTL3 SYTL4 SYTL5 UNC13D ZBTB16	72 interacting genes: AMOT ANXA7 APLP1 ATPAF2 BID BTBD2 CCDC106 CCDC57 CDK5RAP2 CDKN1A CDKN2C COX17 COX5B CSTPP1 EIF1AD ERH FAM118B FAM90A1 FXYD6 GADD45G GLYAT GSE1 GSTO1 GYS1 HSF2BP HSPB1 HSPB3 ID2 JMY KIF9 KPNA2 MAFG MAP7D1 MLH1 MLLT3 MNAT1 MPHOSPH6 NTAQ1 NUDT21 OSGEP PAFAH1B3 PCDHA4 PIBF1 PNP POLR1C PPP1R8 PRG2 PRKAB2 PSMD11 RAB27A RAD51D RFC5 RPA2 S100Z SAT1 SCNM1 SERPINB9 SH3GL3 SMN1 SPRED2 SULT1E1 TAF9 TBC1D22B TEKT4 TK1 TNFSF10 TRDMT1 TRIB3 TSR2 VIM WDR33 ZNF24
Entrez ID		5873	84060
HPRD ID		04845	13173
Ensembl ID		ENSG00000069974	ENSG00000127993
Uniprot IDs		A2RU94 P51159	Q5RL73
PDB IDs		6HUF 7OPP 7OPQ 7OPR 8P3G 8P3H 8P3I 8P3J 8P3K	7DVQ
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Intracellular Transport Establishment Of Localization In Cell Secretion By Cell Exocytosis Intracellular Protein Transport Cellular Localization Protein Transport Exocytic Vesicle Vesicle-mediated Transport Neurexin Family Protein Binding Secretion Establishment Of Protein Localization Intracellular Protein Localization Regulation Of Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Exocytosis Modulation Of Excitatory Postsynaptic Potential Regulation Of Secretion By Cell Regulation Of Secretion Regulation Of Regulated Secretory Pathway Regulation Of Vesicle-mediated Transport Positive Regulation Of Secretion By Cell Vesicle Docking Involved In Exocytosis Melanosome Positive Regulation Of Secretion Synaptic Vesicle Docking Positive Regulation Of Regulated Secretory Pathway Regulation Of Nervous System Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Calcium Ion-dependent Exocytosis Synaptic Vesicle Priming Vesicle Docking Regulation Of Transport Signal Release Organelle Localization By Membrane Tethering Organelle Localization Myosin Binding Positive Regulation Of Establishment Of Protein Localization Membrane Docking Regulation Of Hormone Levels Neurotransmitter Transport Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Regulated Exocytosis Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Transport Protein Localization To Extracellular Region	Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle
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