RAB27A and RBM48

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAB27A	RBM48
Gene Name		RAB27A, member RAS oncogene family	RNA binding motif protein 48
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Lysosome Late Endosome Golgi Apparatus Apical Plasma Membrane Secretory Granule Dendrite Secretory Granule Membrane Multivesicular Body Membrane Melanosome Extracellular Vesicular Exosome Exocytic Vesicle	Nucleoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	RNA Binding
	Biological Process	Protein Targeting Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Blood Coagulation Protein Secretion Positive Regulation Of Gene Expression Antigen Processing And Presentation Melanocyte Differentiation Melanosome Localization Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Organization Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Cellular Protein Metabolic Process Positive Regulation Of Exocytosis Synaptic Vesicle Transport Positive Regulation Of Phagocytosis Multivesicular Body Sorting Pathway Complement-dependent Cytotoxicity Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Constitutive Secretory Pathway Exosomal Secretion
Pathways		Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ADRB2 APP C14orf1 COPS6 EEF1A1 EXPH5 GDF9 GDI1 GZMB KIAA1377 LRIF1 MLPH MYO5A MYRIP RABGGTB RBM48 RIMS1 RIMS2 RPH3A RPH3AL STX1A SYTL1 SYTL2 SYTL3 SYTL4 SYTL5 UNC13D ZBTB16	50 interactors: ANXA7 APLP1 BID BTBD2 C11orf49 CCDC106 CDK5RAP2 CDKN1A CDKN2C COX17 ERH FAM118B FXYD6 GADD45G GLYAT GSE1 GSTO1 HSPB1 HSPB3 ID2 KPNA2 MAFG MAP7D1 MLLT3 MNAT1 MPHOSPH6 NUDT21 OSGEP PAFAH1B3 PCDHA4 PNP PPP1R8 PRG2 PSMD11 RAB27A RFC5 RPA2 SAT1 SERPINB9 SH3GL3 SMN1 SULT1E1 TAF9 TK1 TNFSF10 TRDMT1 TRIB3 VIM WDR33 ZNF24
Entrez ID		5873	84060
HPRD ID		04845	13173
Ensembl ID		ENSG00000069974	ENSG00000127993
Uniprot IDs		A2RU94 P51159	B4DGJ6 B7Z2K5 Q5RL73
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis Secretion By Cell Intracellular Transport Secretion Cellular Protein Localization Establishment Of Localization In Cell Cellular Localization Protein Transport Intracellular Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Regulation Of Secretion Regulation Of Cellular Localization Regulation Of Exocytosis Positive Regulation Of Secretion Transport Positive Regulation Of Exocytosis Positive Regulation Of Transport Regulation Of Vesicle-mediated Transport Regulation Of Establishment Of Protein Localization Multivesicular Body Sorting Pathway Positive Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Positive Regulation Of Membrane Potential Calcium Ion-dependent Exocytosis Regulation Of Protein Localization Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Protein Transport Positive Regulation Of Protein Secretion Regulation Of Protein Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Vesicle Localization Regulation Of Postsynaptic Membrane Potential Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Hormone Secretion Neurotransmitter Secretion Regulation Of Signaling Membrane Depolarization Glutamate Secretion Positive Regulation Of Protein Transport Regulation Of Neurotransmitter Levels Membrane Hyperpolarization Melanocyte Differentiation Neurotransmitter Transport Melanosome Localization Visual Perception Sensory Perception Of Light Stimulus Insulin Secretion Organelle Localization	Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Developmental Process Response To Stimulus Central Nervous System Development MRNA Polyadenylation Nucleoside Metabolic Process Negative Regulation Of Transferase Activity RNA Polyadenylation Regulation Of Cell Cycle Negative Regulation Of Protein Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Apoptotic Process Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Kinase Activity Regulation Of Cell Cycle Phase Transition Response To Stress Negative Regulation Of Catalytic Activity Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death MRNA Processing Multicellular Organismal Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Regulation Of Cellular Protein Metabolic Process Nervous System Development Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Mitotic Cell Cycle Process Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Protein Phosphorylation Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Response To Stress Positive Regulation Of Cell Cycle Arrest
Tagcloud ?		adenocarcinoma aggressive benign cancerous carcinomas deadly ductal exosome gtpases hypothesized immunohistochemistry implicated invasion invasive malignancies member microarray microenvironment modulating pancreatic pdac regulating represent secretion tissues tp53 trafficking vesicle
Tagcloud (Difference) ?		adenocarcinoma aggressive benign cancerous carcinomas deadly ductal exosome gtpases hypothesized immunohistochemistry implicated invasion invasive malignancies member microarray microenvironment modulating pancreatic pdac regulating represent secretion tissues tp53 trafficking vesicle
Tagcloud (Intersection) ?