RAB27A and SYTL1

Number of citations of the paper that reports this interaction (PMID 11980908)
70

Data Source:
HPRD (in vivo, in vitro)

		RAB27A	SYTL1
Gene Name		RAB27A, member RAS oncogene family	synaptotagmin-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Lysosome Late Endosome Golgi Apparatus Apical Plasma Membrane Secretory Granule Dendrite Secretory Granule Membrane Multivesicular Body Membrane Melanosome Extracellular Vesicular Exosome Exocytic Vesicle	Plasma Membrane Extrinsic Component Of Plasma Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Protein Binding Rab GTPase Binding Neurexin Family Protein Binding
	Biological Process	Protein Targeting Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Blood Coagulation Protein Secretion Positive Regulation Of Gene Expression Antigen Processing And Presentation Melanocyte Differentiation Melanosome Localization Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Organization Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Cellular Protein Metabolic Process Positive Regulation Of Exocytosis Synaptic Vesicle Transport Positive Regulation Of Phagocytosis Multivesicular Body Sorting Pathway Complement-dependent Cytotoxicity Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Constitutive Secretory Pathway Exosomal Secretion	Intracellular Protein Transport Exocytosis
Pathways		Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ADRB2 APP C14orf1 COPS6 EEF1A1 EXPH5 GDF9 GDI1 GZMB KIAA1377 LRIF1 MLPH MYO5A MYRIP RABGGTB RBM48 RIMS1 RIMS2 RPH3A RPH3AL STX1A SYTL1 SYTL2 SYTL3 SYTL4 SYTL5 UNC13D ZBTB16	6 interactors: NCF1 NCF2 NRXN1 RAB27A RAB27B RAB8A
Entrez ID		5873	84958
HPRD ID		04845	12156
Ensembl ID		ENSG00000069974	ENSG00000142765
Uniprot IDs		A2RU94 P51159	Q8IYJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis Secretion By Cell Intracellular Transport Secretion Cellular Protein Localization Establishment Of Localization In Cell Cellular Localization Protein Transport Intracellular Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Regulation Of Secretion Regulation Of Cellular Localization Regulation Of Exocytosis Positive Regulation Of Secretion Transport Positive Regulation Of Exocytosis Positive Regulation Of Transport Regulation Of Vesicle-mediated Transport Regulation Of Establishment Of Protein Localization Multivesicular Body Sorting Pathway Positive Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Positive Regulation Of Membrane Potential Calcium Ion-dependent Exocytosis Regulation Of Protein Localization Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Protein Transport Positive Regulation Of Protein Secretion Regulation Of Protein Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Vesicle Localization Regulation Of Postsynaptic Membrane Potential Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Hormone Secretion Neurotransmitter Secretion Regulation Of Signaling Membrane Depolarization Glutamate Secretion Positive Regulation Of Protein Transport Regulation Of Neurotransmitter Levels Membrane Hyperpolarization Melanocyte Differentiation Neurotransmitter Transport Melanosome Localization Visual Perception Sensory Perception Of Light Stimulus Insulin Secretion Organelle Localization	Vesicle Localization Multivesicular Body Sorting Pathway Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Organelle Localization Protein Secretion Secretion By Cell Cellular Protein Localization Respiratory Burst Regulation Of Exocytosis Establishment Of Protein Localization Superoxide Anion Generation Secretion Regulation Of Secretion Establishment Of Vesicle Localization Ras Protein Signal Transduction Protein Localization Leukocyte Mediated Cytotoxicity Establishment Of Localization In Cell Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Intracellular Protein Transport Antigen Processing And Presentation Melanosome Localization Superoxide Metabolic Process Establishment Of Organelle Localization Regulation Of Cellular Localization Phagosome Maturation Exocytosis Cellular Localization Protein Localization To Membrane Cellular Defense Response Regulation Of Vesicle-mediated Transport Cellular Pigmentation Positive Regulation Of Exocytosis Signal Transduction Protein Transport Signaling Cell Communication Intracellular Transport Positive Regulation Of Constitutive Secretory Pathway Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Complement-dependent Cytotoxicity Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Synaptic Transmission
Tagcloud ?		adenocarcinoma aggressive benign cancerous carcinomas deadly ductal exosome gtpases hypothesized immunohistochemistry implicated invasion invasive malignancies member microarray microenvironment modulating pancreatic pdac regulating represent secretion tissues tp53 trafficking vesicle
Tagcloud (Difference) ?		adenocarcinoma aggressive benign cancerous carcinomas deadly ductal exosome gtpases hypothesized immunohistochemistry implicated invasion invasive malignancies member microarray microenvironment modulating pancreatic pdac regulating represent secretion tissues tp53 trafficking vesicle
Tagcloud (Intersection) ?