RBM48 and MPHOSPH6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM48	MPHOSPH6
Gene Name		RNA binding motif protein 48	M-phase phosphoprotein 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Binding	RNA Binding Protein Binding
	Biological Process		Maturation Of 5.8S RRNA
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		50 interactors: ANXA7 APLP1 BID BTBD2 C11orf49 CCDC106 CDK5RAP2 CDKN1A CDKN2C COX17 ERH FAM118B FXYD6 GADD45G GLYAT GSE1 GSTO1 HSPB1 HSPB3 ID2 KPNA2 MAFG MAP7D1 MLLT3 MNAT1 MPHOSPH6 NUDT21 OSGEP PAFAH1B3 PCDHA4 PNP PPP1R8 PRG2 PSMD11 RAB27A RFC5 RPA2 SAT1 SERPINB9 SH3GL3 SMN1 SULT1E1 TAF9 TK1 TNFSF10 TRDMT1 TRIB3 VIM WDR33 ZNF24	24 interactors: AATF APLP1 ARHGAP18 C14orf1 DNM2 DYNLRB1 EIF3G EXOSC10 FTL GDF9 KNSTRN LRIF1 NUPR1 PARN RBM48 RPS20 SKIV2L2 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1
Entrez ID		84060	10200
HPRD ID		13173	16111
Ensembl ID		ENSG00000127993	ENSG00000135698
Uniprot IDs		B4DGJ6 B7Z2K5 Q5RL73	Q99547
PDB IDs
Enriched GO Terms of Interacting Partners?		Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Developmental Process Response To Stimulus Central Nervous System Development MRNA Polyadenylation Nucleoside Metabolic Process Negative Regulation Of Transferase Activity RNA Polyadenylation Regulation Of Cell Cycle Negative Regulation Of Protein Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Apoptotic Process Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Kinase Activity Regulation Of Cell Cycle Phase Transition Response To Stress Negative Regulation Of Catalytic Activity Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death MRNA Processing Multicellular Organismal Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Regulation Of Cellular Protein Metabolic Process Nervous System Development Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Mitotic Cell Cycle Process Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Protein Phosphorylation Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Response To Stress Positive Regulation Of Cell Cycle Arrest	Gene Expression RNA Metabolic Process Regulation Of Female Gonad Development Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Maturation Of 5.8S RRNA Positive Regulation Of Protein Oligomerization Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Endocytosis Regulation Of Protein Oligomerization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Negative Regulation Of Cell Growth MRNA Catabolic Process Negative Regulation Of Fibroblast Proliferation Nitrogen Compound Metabolic Process Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Cell Division Regulation Of Gene Expression RNA Catabolic Process Ribosome Biogenesis Regulation Of Metabolic Process Mitotic Cytokinesis Negative Regulation Of Reactive Oxygen Species Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Membrane Organization Growth Negative Regulation Of Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Growth Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Processing Regulation Of Apoptotic Process Negative Regulation Of Macromitophagy Negative Regulation Of Membrane Tubulation Lipid Tube Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Negative Regulation Of Caveolin-mediated Endocytosis Oocyte Growth
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