RBM48 and PRG2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM48	PRG2
Description		RNA binding motif protein 48	proteoglycan 2, pro eosinophil major basic protein
Image
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Extracellular Region Transport Vesicle Extracellular Matrix Cytoplasmic Vesicle Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	Protein Binding Heparin Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance Carbohydrate Binding
	Biological Process	MRNA Processing RNA Splicing	Defense Response To Nematode Immune System Process Immune Response Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-4 Production Defense Response To Bacterium
Pathways			Neutrophil degranulation
Drugs			Sargramostim Chymopapain
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Idiopathic dilated cardiomyopathy ( 29495422)	Crohn's disease ( 22412388) Glucose homeostasis traits ( 25524916)
Interacting Genes		72 interacting genes: AMOT ANXA7 APLP1 ATPAF2 BID BTBD2 CCDC106 CCDC57 CDK5RAP2 CDKN1A CDKN2C COX17 COX5B CSTPP1 EIF1AD ERH FAM118B FAM90A1 FXYD6 GADD45G GLYAT GSE1 GSTO1 GYS1 HSF2BP HSPB1 HSPB3 ID2 JMY KIF9 KPNA2 MAFG MAP7D1 MLH1 MLLT3 MNAT1 MPHOSPH6 NTAQ1 NUDT21 OSGEP PAFAH1B3 PCDHA4 PIBF1 PNP POLR1C PPP1R8 PRG2 PRKAB2 PSMD11 RAB27A RAD51D RFC5 RPA2 S100Z SAT1 SCNM1 SERPINB9 SH3GL3 SMN1 SPRED2 SULT1E1 TAF9 TBC1D22B TEKT4 TK1 TNFSF10 TRDMT1 TRIB3 TSR2 VIM WDR33 ZNF24	7 interacting genes: AGT AKT1 CHD3 CSF2 PAPPA PRKCZ RBM48
Entrez ID		84060	5553
HPRD ID		13173	09283
Ensembl ID		ENSG00000127993	ENSG00000186652
Uniprot IDs		Q5RL73	P13727
PDB IDs		7DVQ	1H8U 2BRS 4QXX 7Y5N 8HGG 9DKZ
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Metabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cell Differentiation Positive Regulation Of Steroid Metabolic Process Response To Fluid Shear Stress Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cholesterol Metabolic Process Response To Peptide Hormone Positive Regulation Of Cell Differentiation Regulation Of Sodium Ion Transport Regulation Of Apoptotic Signaling Pathway Regulation Of TRNA Methylation Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Regulation Of Developmental Process Positive Regulation Of Cytokine Production Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Membrane Potential Response To Hormone Renin-angiotensin Regulation Of Aldosterone Production Negative Regulation Of Signaling Positive Regulation Of Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Growth Factor Activity Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Developmental Process Positive Regulation Of Endothelial Cell Migration Regulation Of Lipid Transport Positive Regulation Of Membrane Hyperpolarization Regulation Of Programmed Cell Death Positive Regulation Of Locomotion Positive Regulation Of Lipid Metabolic Process Response To Muscle Activity Involved In Regulation Of Muscle Adaptation G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Regulation Of Renal Output By Angiotensin Negative Regulation Of Cell Communication Positive Regulation Of Macromolecule Biosynthetic Process Type 2 Angiotensin Receptor Binding Negative Regulation Of Transmembrane Transport Regulation Of Steroid Metabolic Process Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Organelle Assembly
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