RBM48 and PRG2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM48	PRG2
Gene Name		RNA binding motif protein 48	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Extracellular Region Transport Vesicle Extracellular Vesicular Exosome
	Molecular Function	RNA Binding	Heparin Binding Carbohydrate Binding
	Biological Process		Defense Response To Nematode Immune Response Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-4 Production Defense Response To Bacterium
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 22412388)
Protein-Protein Interactions		50 interactors: ANXA7 APLP1 BID BTBD2 C11orf49 CCDC106 CDK5RAP2 CDKN1A CDKN2C COX17 ERH FAM118B FXYD6 GADD45G GLYAT GSE1 GSTO1 HSPB1 HSPB3 ID2 KPNA2 MAFG MAP7D1 MLLT3 MNAT1 MPHOSPH6 NUDT21 OSGEP PAFAH1B3 PCDHA4 PNP PPP1R8 PRG2 PSMD11 RAB27A RFC5 RPA2 SAT1 SERPINB9 SH3GL3 SMN1 SULT1E1 TAF9 TK1 TNFSF10 TRDMT1 TRIB3 VIM WDR33 ZNF24	7 interactors: AGT AKT1 CHD3 CSF2 PAPPA PRKCZ RBM48
Entrez ID		84060	5553
HPRD ID		13173	09283
Ensembl ID		ENSG00000127993
Uniprot IDs		B4DGJ6 B7Z2K5 Q5RL73	A6XMW0 P13727
PDB IDs			1H8U 2BRS
Enriched GO Terms of Interacting Partners?		Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Developmental Process Response To Stimulus Central Nervous System Development MRNA Polyadenylation Nucleoside Metabolic Process Negative Regulation Of Transferase Activity RNA Polyadenylation Regulation Of Cell Cycle Negative Regulation Of Protein Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Apoptotic Process Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Kinase Activity Regulation Of Cell Cycle Phase Transition Response To Stress Negative Regulation Of Catalytic Activity Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death MRNA Processing Multicellular Organismal Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Regulation Of Cellular Protein Metabolic Process Nervous System Development Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Mitotic Cell Cycle Process Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Protein Phosphorylation Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Response To Stress Positive Regulation Of Cell Cycle Arrest	Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Cellular Ketone Metabolic Process Cell Activation Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Peptidyl-tyrosine Phosphorylation Female Pregnancy Positive Regulation Of Cell Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Glucose Import Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Cell Death Positive Regulation Of Glucose Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Protein Phosphorylation Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Signal Transduction Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transmembrane Transport Regulation Of Glucose Import Positive Regulation Of Endothelial Cell Migration Regulation Of Vasoconstriction Negative Regulation Of Signaling Negative Regulation Of Hydrolase Activity Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Lipid Biosynthetic Process Positive Regulation Of Protein Metabolic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Sodium Ion Transport Positive Regulation Of Signal Transduction Positive Regulation Of Phospholipase Activity Regulation Of Phosphorylation Reproductive Process Cellular Response To Mechanical Stimulus Positive Regulation Of Protein Kinase Activity Regulation Of Phospholipase Activity Regulation Of Oxidoreductase Activity Developmental Cell Growth Positive Regulation Of Peptidyl-serine Phosphorylation
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