RBM48 and MLLT3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM48	MLLT3
Description		RNA binding motif protein 48	MLLT3 super elongation complex subunit
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Chromosome Cytosol Transcription Elongation Factor Complex Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	DNA Binding Chromatin Binding Protein Binding Histone Binding Molecular Adaptor Activity Modification-dependent Protein Binding Histone H3K18ac Reader Activity Histone H3K9ac Reader Activity Histone H3K27ac Reader Activity
	Biological Process	MRNA Processing RNA Splicing	Chromatin Organization Segment Specification Anterior/posterior Pattern Specification Gene Expression Positive Regulation Of DNA-templated Transcription Hematopoietic Stem Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Chromatin Organization Regulation Of Stem Cell Division Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Idiopathic dilated cardiomyopathy ( 29495422)	Atrial fibrillation ( 29892015) Dietary fat liking ( 32516399) Estimated glomerular filtration rate ( 31152163) Glutathione peroxidase in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Platelet distribution width ( 32888494) Response to montelukast in asthma (change in FEV1) ( 26083242) Systolic blood pressure ( 30578418)
Interacting Genes		72 interacting genes: AMOT ANXA7 APLP1 ATPAF2 BID BTBD2 CCDC106 CCDC57 CDK5RAP2 CDKN1A CDKN2C COX17 COX5B CSTPP1 EIF1AD ERH FAM118B FAM90A1 FXYD6 GADD45G GLYAT GSE1 GSTO1 GYS1 HSF2BP HSPB1 HSPB3 ID2 JMY KIF9 KPNA2 MAFG MAP7D1 MLH1 MLLT3 MNAT1 MPHOSPH6 NTAQ1 NUDT21 OSGEP PAFAH1B3 PCDHA4 PIBF1 PNP POLR1C PPP1R8 PRG2 PRKAB2 PSMD11 RAB27A RAD51D RFC5 RPA2 S100Z SAT1 SCNM1 SERPINB9 SH3GL3 SMN1 SPRED2 SULT1E1 TAF9 TBC1D22B TEKT4 TK1 TNFSF10 TRDMT1 TRIB3 TSR2 VIM WDR33 ZNF24	18 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 EEF1A1 H3C1 LRIF1 LRRK2 MCM6 NRIP1 PTN RBM48 SGK1 VAX1 ZNF572
Entrez ID		84060	4300
HPRD ID		13173	01163
Ensembl ID		ENSG00000127993	ENSG00000171843
Uniprot IDs		Q5RL73	A0A0S2Z448 P42568
PDB IDs		7DVQ	2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6L5Z 6LS6 6MIL 6MIM 7EIC 7EID 7VKG 7VKH 8PJ7 8TLV 8TLW 8TLX 9ARO 9ARR
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cell Projection Morphogenesis Golgi-associated Vesicle Chromatin Organization Epigenetic Regulation Of Gene Expression Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Neuron Projection Morphogenesis Regulation Of Gene Expression Negative Regulation Of Long-term Synaptic Potentiation Response To Auditory Stimulus Cellular Response To Catecholamine Stimulus Regulation Of Metabolic Process Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Nucleoplasm Regulation Of Neuroblast Proliferation Neuron Projection Arborization Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Neuroblast Proliferation Nuclear Retinoic Acid Receptor Binding Negative Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Memory Molecular Function Activator Activity Negative Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of RNA Metabolic Process Chromatin Remodeling Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Metabolic Process Dendrite Development Cyclin D2-CDK6 Complex Response To Polyamine Macromolecule Response To Reactive Oxygen Species Ovarian Follicle Rupture DNA N6-methyladenine Demethylase Activity Negative Regulation Of Tooth Mineralization BCOR Complex
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