RAB1A and CHM

Number of citations of the paper that reports this interaction (PMID 8294464)
30

Data Source:
BioGRID (enzymatic study, pull down)

		RAB1A	CHM
Gene Name		RAB1A, member RAS oncogene family	choroideremia (Rab escort protein 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Early Endosome Endoplasmic Reticulum Membrane Cytosol Melanosome Extracellular Vesicular Exosome	Cytosol Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Rab Geranylgeranyltransferase Activity GTPase Activator Activity Rab GTPase Binding
	Biological Process	Autophagic Vacuole Assembly Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Cilium Assembly Defense Response To Bacterium Vesicle Transport Along Microtubule Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process	Blood Vessel Development Protein Targeting To Membrane Visual Perception Protein Geranylgeranylation Positive Regulation Of GTPase Activity Response To Stimulus
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ADCK1 CAPNS1 CDKN1A CHM CHML CREB1 FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SYT5 TBC1D17 USO1 ZNF593	13 interactors: RAB14 RAB18 RAB1A RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5A RAB5B RAB6A RAB7A
Entrez ID		5861	1121
HPRD ID		01538	02312
Ensembl ID		ENSG00000138069	ENSG00000188419
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	P24386
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?		Protein Geranylgeranylation Protein Prenylation Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Membrane Fusion Positive Regulation Of Metabolic Process Protein Transport Establishment Of Protein Localization Visual Perception Sensory Perception Of Light Stimulus Slow Endocytic Recycling Riboflavin Biosynthetic Process FMN Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Membrane Organization Positive Regulation Of Microtubule Plus-end Binding Golgi Vesicle Docking Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cell Cycle Positive Regulation Of Cell Cycle Arrest Cellular Process Positive Regulation Of NAD(P)H Oxidase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Apoptotic Process Protein Localization Vesicle-mediated Transport Programmed Cell Death Signal Transduction In Response To DNA Damage Establishment Of Localization In Cell Mitotic DNA Damage Checkpoint Cell Death Death Intestinal Epithelial Cell Maturation Riboflavin Metabolic Process Regulation Of Cell Cycle Arrest Intracellular Transport Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint	Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Cellular Localization Cytoplasmic Transport Peptidyl-cysteine Methylation Vesicle-mediated Transport Regulation Of Vesicle-mediated Transport Endosomal Transport Transport Signal Transduction Antigen Processing And Presentation Signaling Cell Communication Regulation Of Exocytosis Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Cellular Response To Stimulus Membrane Docking Synaptic Vesicle Transport Protein Secretion Establishment Of Organelle Localization Response To Stimulus Phagosome Maturation Organelle Localization Synaptic Vesicle Exocytosis Vesicle Docking Involved In Exocytosis Golgi Vesicle Transport Vesicle Docking Regulation Of Secretion Endocytosis Positive Regulation Of Secretion Phagolysosome Assembly Vacuole Organization Neurotransmitter Secretion Positive Regulation Of Transport Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly Regulation Of Vacuole Organization Positive Regulation Of Regulated Secretory Pathway
Tagcloud ?		added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping	androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity
Tagcloud (Difference) ?		added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping	androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity
Tagcloud (Intersection) ?